What does vitamin k do for newborns

FAQs About Vitamin K Deficiency Bleeding

Since 1961, the American Academy of Pediatrics has recommended supplementing low levels of vitamin K in newborns with a single shot of vitamin K given at birth.  Low levels of vitamin K can lead to dangerous bleeding in newborns and infants.  The vitamin K given at birth provides protection against bleeding that could occur because of low levels of this essential vitamin.   

Below are some commonly asked questions and their answers.   If you continue to have concerns about vitamin K, please talk to your pediatrician or healthcare provider.

Q: What is vitamin K, and how do low levels of vitamin K and vitamin K deficiency bleeding occur in babies?

A: Vitamin K is used by the body to form clots and to stop bleeding. Babies are born with very little vitamin K stored in their bodies. This is called “vitamin K deficiency” and means that a baby has low levels of vitamin K.  Without enough vitamin K, babies cannot make the substances used to form clots, called ‘clotting factors.’  When bleeding happens because of low levels of vitamin K, this is called “vitamin K deficiency bleeding” or VKDB. VKDB is a serious and potentially life-threatening cause of bleeding in infants up to 6 months of age. A vitamin K shot given at birth is the best way to prevent low levels of vitamin K and vitamin K deficiency bleeding (VKDB).

Q: Why do ALL babies need a vitamin K shot – can’t I just wait to see if my baby needs it?

A:  No, waiting to see if your baby needs a vitamin K shot may be too late.  Babies can bleed into their intestines or brain where parents can’t see the bleeding to know that something is wrong. This can delay medical care and lead to serious and life-threatening consequences. All babies are born with very low levels of vitamin K because it doesn’t cross the placenta well. Breast milk contains only small amounts of vitamin K. That means that ALL newborns have low levels of vitamin K, so they need vitamin K from another source.  A vitamin K shot is the best way to make sure all babies have enough vitamin K. Newborns who do not get a vitamin K shot are 81 times more likely to develop severe bleeding than those who get the shot.

Q: Doesn’t the risk of bleeding from low levels of vitamin K only last a few weeks?

A:  No, VKDB can happen to otherwise healthy babies up to 6 months of age.  The risk isn’t limited to just the first 7 or 8 days of life and VKDB doesn’t just happen to babies who have difficult births. In 2013, the Centers for Disease Control and Prevention (CDC) investigated 4 cases of infants with bleeding from low levels of vitamin K.  All four were over 6 weeks old when the bleeding started and they had been healthy and developing normally.  None of them had received a vitamin K shot at birth.

Q: Isn’t VKDB really rare?

A:  VKDB is rare in the United States, but only because most newborns get the vitamin K shot. Over the past two decades, many countries in Europe have started programs to provide vitamin K at birth – afterward, they all saw declines in the number of cases of VKDB to very low levels.  However, in areas of the world where the vitamin K shot isn’t available, VKDB is more common, and many cases of VKDB have been reported from these countries

In the early 1980s in England, some hospitals started giving vitamin K only to newborns that were thought to be at higher risk for bleeding.  They then noticed an increase in cases of VKDB.  This tells us that giving vitamin K to prevent bleeding is what keeps VKDB a rare condition – when vitamin K is not given to newborns, cases of bleeding occur and VKDB stops being rare.

Q: What happens when babies have low levels of vitamin K and get VKDB?

A: Babies without enough vitamin K cannot form clots to stop bleeding and they can bleed anywhere in their bodies. The bleeding can happen in their brains or other important organs and can happen quickly. Even though bleeding from low levels of vitamin K or VKDB does not occur often in the United States, it is devastating when it does occur. One out of every five babies with VKDB dies.  Of the infants who have late VKDB, about half of them have bleeding into their brains, which can lead to permanent brain damage.  Others bleed in their stomach or intestines, or in other parts of the body.  Many of the infants need blood transfusions, and some need surgeries.

Q: I heard that the vitamin K shot might cause cancer.  Is this true?

A: No. In the early 1990s, a small study in England found an “association” between the vitamin K shot and childhood cancer.  An association means that two things are happening at the same time in the same person, but doesn’t tell us whether one causes the other.  Figuring out whether vitamin K might cause childhood cancer was very important because every newborn is expected to get a vitamin K shot. If vitamin K was causing cancer, we would expect to see the same association in other groups of children. Scientists looked to see if they could find the same association in other children, but this association between vitamin K and childhood cancer was never found again in any other study.

Q: Can the other ingredients in the shot cause problems for my baby?  Do we really know that the vitamin K shot is safe?

A: Yes, the vitamin K shot is safe. Vitamin K is the main ingredient in the shot. The other ingredients make the vitamin K safe to give as a shot. One ingredient keeps the vitamin K mixed in the liquid; another keeps the liquid from being too acidic.  One of the ingredients is benzyl alcohol, a preservative.  Benzyl alcohol is a common ingredient in many medications.

In the 1980s, doctors recognized that very premature infants who were in neonatal intensive care units might become sick from benzyl alcohol toxicity because many of the medicines and fluids needed for their intensive care contained benzyl alcohol as a preservative.   Although the toxicity was only reported for very premature infants, since then doctors have tried to minimize the amount of benzyl-alcohol-containing medications they give.   Clearly, the small amount of benzyl alcohol in the vitamin K shot is not enough to be dangerous, even when given in combination with other medications that also contain small amounts of this preservative.

Q: The dose of the shot seems high.  Is that too much for my baby?

A: No, the dose in the vitamin K shot is not too much for babies. The dose of vitamin K in the shot is high compared to the daily requirement of vitamin K. But remember babies don’t have much vitamin K when they are born and won’t have a good supply of vitamin K until they are close to six months old.  This is because vitamin K does not cross the placenta and breast milk has very low levels of vitamin K.

The vitamin K shot acts in two ways to increase the vitamin K levels. First, part of the vitamin K goes into the infant’s bloodstream immediately and increases the amount of vitamin K in the blood. This provides enough vitamin K so that the infant’s levels don’t drop dangerously low in the first few days of life.  Much of this vitamin K gets stored in the liver and it is used by the clotting system.  Second, the rest of the vitamin K is released slowly over the next 2-3 months, providing a steady source of vitamin K until an infant has another source from his or her diet.

Q: Can I increase vitamin K in my breast milk by eating different foods or taking multivitamins or vitamin K supplements?

A: We encourage moms to eat healthy and take multivitamins as needed. Although eating foods high in vitamin K or taking vitamin K supplements can slightly increase the levels of vitamin K in your breast milk, neither can increase levels in breast milk enough to provide all of the vitamin K an infant needs.

When infants are born, their already low levels of vitamin K fall even lower.  Infants need enough vitamin K to (a) make up for their extra-low levels, (b) start storing it in the liver for future use, and (c) ensure good bone and blood health.   Breast milk – even from mothers supplementing with vitamin K sources – can’t provide enough to do all of these things.

Q: My baby is so little. What can I do to make the vitamin K shot less painful and traumatic?

A: Babies, just like us, feel pain, and it is important to reduce even small amounts of discomfort. Babies feel less pain from shots if they are held and allowed to suck.You can ask to hold your baby while the vitamin K shot is given so that your baby can be comforted by you. Breastfeeding while the shot is given and immediately after can be comforting too.  All of these are things parents can do to ease pain and soothe their baby.

Remember that if your baby does not get the vitamin K shot, his or her risk of developing severe bleeding is 81 times higher than if he or she got the shot.  Diagnosis and treatment of VKDB often involves many painful procedures, including repeated blood draws.

Q: Overall, what are the risks and benefits of the vitamin K shot?

The risks of the vitamin K shot are the same risks that are part of getting most any other shot.  These include pain or even bruising or swelling at the place where the shot is given.  A few cases of skin scarring at the site of injection have been reported. Only a single case of allergic reaction in an infant has been reported, so this is extremely rare.

Although there have been concerns about some other risks, like a risk for childhood cancer or risks because of additional ingredients, none of these risks have been proven by scientific studies.

The main benefit of the vitamin K shot is that it can protect your baby from VKDB, a dangerous condition that can cause long-term disability or death.  In addition, the diagnosis and treatment of VKDB often includes multiple and sometimes painful procedures, such as blood draws, CT scans, blood transfusions, or anesthesia and surgery.

The American Academy of Pediatrics has recommended the Vitamin K shot since 1961, and has repeatedly stood by that recommendation because the risks of the shot don’t outweigh the risks of VKDB, which are based on decades of evidence and decades of experience with babies who were hospitalized or died from VKDB.

Your child’s doctor is the best person to talk to about vitamin K.  Like you, your child’s doctor wants to see your children grow up safe and healthy and wants to support your efforts to make the best decisions for their health.  If you have concerns about vitamin K, talk to your child’s doctor.

Vitamin K at birth | Pregnancy Birth and Baby

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Key facts

• Vitamin K helps your baby’s blood to clot.
• Babies need more vitamin K than they get from their mother during pregnancy or from breast milk.
• Parents of all newborns are offered a vitamin K injection for their baby soon after birth.
• This helps prevent babies from becoming vitamin K deficient.
• Without the injection, they are at risk of developing a condition called Vitamin K Deficiency Bleeding (known as VKDB).

What is vitamin K?

Vitamin K is an essential vitamin, and has an important role in maintaining good health by helping blood to clot. Vitamin K helps prevent serious bleeding.

Why is vitamin K important for my baby?

Vitamin K helps your baby’s blood clot and prevents serious bleeding. Babies do not get enough vitamin K naturally from their mother during pregnancy. Breast milk also does not provide babies with enough levels of vitamin K. This can result in vitamin K deficiency in newborns.

If your baby has vitamin K deficiency, they are at risk of developing a disease called Vitamin K Deficiency Bleeding, or VKDB. While VKDB is rare, it can be very serious as it can cause babies to bleed excessively and may cause them to bleed into their brain. This condition may result in brain damage and even death.

How is vitamin K given?

Vitamin K is usually given as a single injection in your baby’s leg muscle shortly after birth. If you prefer that your baby does not get an injection, they can have liquid vitamin K drops into their mouth. It is important to note that oral vitamin K drops are not absorbed as well by the body than injected vitamin K, so 3 doses of oral vitamin K are needed. The first dose is given at birth, the second at 3 to 5 days of age and the third when they are 4 weeks old.

Vitamin K injections are preferred over the oral drops for all babies. Some babies aren’t able to have oral vitamin K, such as if the mother was taking certain medications while pregnant, or if your baby is premature, unwell, taking antibiotics or has diarrhoea.

Can all babies have vitamin K?

Yes, all babies can have vitamin K. If your baby is premature or very small, they might need a smaller dose of vitamin K. You can discuss this with your doctor.

How much does vitamin K cost?

Vitamin K injections or drops are free. The cost is covered by the government for all babies born in Australia.

Does vitamin K have any side effects? What should I look out for?

Vitamin K in newborns is not associated with any side effects, and has been given to Australian babies for more than 30 years. Studies have investigated whether there is an association between injected vitamin K and childhood cancers. Doctors and scientists have concluded that vitamin K injections are safe and beneficial for babies, and that there is no link between vitamin K and childhood cancer.

If your baby has not had a vitamin K injection or the full 3-dose course of vitamin K oral drops it is important that you look out for:

• unexplained bleeding or bruising
• showing signs of jaundice after they are 3 weeks old

If they show any of these symptoms, see your doctor or midwife immediately.

If your baby has liver problems, they may be at a higher risk of bleeding, even if they have had their recommended dose of vitamin K.

Does my baby need to have vitamin K?

It is your choice whether to give your baby vitamin K or not. However, giving vitamin K to your newborn is an easy way to prevent a very serious disease. Health authorities in Australia and throughout the world recommend giving vitamin K to all newborn babies — even babies who were born prematurely or are sick.

How do I get vitamin K for my baby?

During your pregnancy your doctor or midwife will talk to you about vitamin K, including the pros and cons of giving your baby vitamin K by injection or by mouth. Your doctor or midwife will then note this on your file. Your baby will receive vitamin K soon after birth by a doctor or a midwife, based on your decision.

If you have chosen to give your baby vitamin K by mouth then your baby will need to receive 2 more doses after the dose they receive at birth. The second dose can be given in hospital at the same time as your baby has their newborn screening test, or by your local doctor or healthcare worker. It is important to remember to arrange your baby’s third dose when they are 4 weeks old. This important final dose can also be given by your doctor or health care worker.

If you are having a home birth, be sure to discuss giving your baby vitamin K with your midwife. Homebirth midwives are required to have all essential equipment available for a planned home birth, including vitamin K injections.

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Last reviewed: June 2022

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Vitamin K for newborns | NHMRC

Vitamin K helps blood to clot and is essential in preventing serious bleeding in infants. Vitamin K deficiency bleeding can be prevented by the administration of vitamin K soon after birth. By the age of approximately six months, infants have built up their own supply of vitamin K.

Read more on NHMRC – National Health and Medical Research Council website