Lice treatment during pregnancy

Head Lice | InfantRisk Center

Pregnancy Breastfeeding

Head lice or Pediculus humanus capitis, attack as many as 12 million children every year. Lice are spread by direct contact with infested hair. Sharing combs, brushes, beds, and hats may also contribute to the spread of these parasites. Lice infestations in the U.S. are more frequent in girls and lead to stigma and absenteeism from school or day care.^{1, 2}

The life cycle of a louse is divided into three stages. The female adult louse lays eggs (nits) that hatch after eight or nine days. The young louse (nymph) matures into adulthood within nine to twelve days. The adult louse usually lives about one month and feeds on human blood. Adult lice are usually tan to grey in color and two to three millimeters in length. Nits are usually yellow to white in color and are less than one millimeter in size. Lice typically die after one or two days without access to a blood meal. Lice do not appear to cause disease but subsequent bacterial infections may occur from scratching.

Signs and symptoms of head lice include tickling on the scalp, difficulty sleeping, and excessive scratching. Diagnosis can be difficult as a louse moves quickly and blends in with the hair shaft. Nits are typically found around 5 millimeters from the scalp during active infestations. All family members should be evaluated for lice if one child has an infestation.

Head lice during pregnancy and breastfeeding can be treated with pediculicides including permethrin, malathion, and ivermectin. There are studies providing evidence that these agents do not increase the risk of birth defects.^3-5 They are also unlikely to pass into the milk of breastfeeding mothers in clinically relevant amounts. Permethrin is preferred for breastfeeding and pregnant mothers because it is non-toxic, and there is minimal absorption through the skin (<2%).⁶ However, at least one additional treatment is usually required to completely treat the infestation.

Newly approved Sklice Lotion (0. 5% ivermectin) may be used in children who are six months and older. A recent study has suggested that a single topical application of ivermectin kills most of the lice.⁷ The researchers found that 94.9% of ivermectin treated patients were louse free one day after application and there was significant reduction in itching between day one and day two in the ivermectin group, as compared with the control group. The proportion of head louse free patients in the ivermectin group was 85.2% on day eight and 73.8% on day fifteen. The continued efficacy of treatment with topical ivermectin two weeks after a single treatment suggests that this formulation has activity against louse eggs. Another recent laboratory study has also suggested this. In this study, ivermectin was applied to head louse ova and, although the ova subsequently hatched, all the released nymphs quickly died. The nymphal mortality was attributed to ivermectin induced mouthpart paralysis, which severely limited or completely prevented the nymphs from feeding. ⁸

Regardless of what medication is used, if any, some careful infection-control measures are necessary to prevent re-infestation. Ova can hide under fingernails and toenails, so careful cleaning and treatment of those areas is important. Wash bedding, clothes, and hats in hot water, and with a hot air cycle in the dryer. Items that cannot be laundered may be dry cleaned or placed in sealed, plastic bags for two weeks to allow time for all lice life cycles to be completed. Vacuuming floors and furniture to remove infested hair is also recommended.

Each involved member of the household should also take time to wet comb their hair. This is a mechanical removal of lice via straining with a fine-toothed comb. Metal combs seem to be more effective than plastic for this purpose. To perform this maneuver, the hair should be wet with an added lubricant such as hair conditioner or olive oil. The hair should be brushed or combed to remove tangles. Insert the comb near the crown of the head until it touches the scalp gently. Draw it firmly down and examine the comb for lice after each stroke. The entire head should be combed systematically at least twice. Repeat the combing until no lice are found in each session.

If no pediculicide is used, repeat sessions may be necessary every three to four days for several weeks. It is somewhat uncertain how effective wet combing is when used in place of topical insecticides. Existing studies have used flawed methodology and have produced contradictory results.

Sonia Shoukat, MD

Thomas W. Hale, Ph.D.

James Abbey, MD

References:

1. Frankowski BL, Weiner LB, Committee on School Health the Committee on Infectious Diseases. American Academy of P. Head lice. Pediatrics. Sep 2002;110(3):638-643
2. Gordon SC. Shared vulnerability: a theory of caring for children with persistent head lice. The Journal of school nursing : the official publication of the National Association of School Nurses. Oct 2007;23(5):283-292
3. Kennedy D, Hurst V, Konradsdottir E, Einarson A. Pregnancy outcome following exposure to permethrin and use of teratogen information. American journal of perinatology. Feb 2005;22(2):87-90
4. Pacque M, Munoz B, Poetschke G, Foose J, Greene BM, Taylor HR. Pregnancy outcome after inadvertent ivermectin treatment during community-based distribution. Lancet. Dec 15 1990;336(8729):1486-1489
5. Thomas DC, Petitti DB, Goldhaber M, Swan SH, Rappaport EB, Hertz-Picciotto I. Reproductive outcomes in relation to malathion spraying in the San Francisco Bay Area, 1981-1982. Epidemiology. Jan 1992;3(1):32-39
6. Pharmaceutical manufacturer prescribing information. 2003
7. Pariser DM, Meinking TL, Bell M, Ryan WG. Topical 0.5% ivermectin lotion for treatment of head lice. The New England journal of medicine. Nov 2012;367(18):1687-1693
8. Strycharz JP, Berge NM, Alves AM, Clark JM. Ivermectin acts as a posteclosion nymphicide by reducing blood feeding of human head lice (Anoplura: Pediculidae) that hatched from treated eggs. Journal of medical entomology. Nov 2011;48(6):1174-118

Common Conditions

Head lice | Pregnancy Birth and Baby

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What are head lice?

Head lice are tiny, wingless insects about the size of a sesame seed that live in the hair of humans and animals. They feed on blood by biting the skin. Their eggs are called nits and are laid in the hair. The nits hatch after several days, producing more lice.

Lice and nits are not dangerous, and do not spread disease, but the bites can cause itching and sometimes skin irritation.

How are head lice spread?

Head lice can be passed between children by contact with personal items, for example shared combs and brushes.

The spread of lice among preschool and school children is common and should not be seen as a sign of poor hygiene.

Lice need warmth and blood to survive. They do not live for long on clothing, bedding or personal items.

What are the symptoms of head lice?

Lice often cause itching of the skin, but this is not always the case. Bites can cause the skin to become red and irritated, which can be made worse by scratching.

You can see the lice and nits if you look closely at your child’s head and scalp. Nits look like tiny white dots attached firmly to the hair. They cannot be brushed or flicked off the hair, but must be physically removed with fingers or fingernails.

How do I know if my child has head lice?

Your child may not have an itchy scalp if they have head lice, and an itchy scalp is not a sure sign of head lice. So the best way to find them is to follow a weekly routine of scalp and hair examination:

1. Using a normal comb, spread hair conditioner through your child’s dry, untangled hair. The hair conditioner briefly stuns the lice to make them easier to catch (lice usually move very quickly, so you might not see them).
2. Using a special metal fine-toothed nit comb (available from the supermarket or chemist), comb sections of hair from the roots to the tips, systematically combing the entire head. Nits and lice become trapped by the fine teeth of the comb.
3. Wipe the conditioner (and lice and nits) from the comb onto a paper towel or tissue.
4. Examine the tissue and the comb for any sign of lice and nits.
5. Repeat the combing to cover the hair on each part of the head twice.
6. If lice or eggs are found, you will need to take steps to treat the head lice to get rid of them.

What is the best treatment for head lice?

The most effective treatment involves repeating the hair conditioner and combing process until no head lice have been found for at least 2 weeks. This covers the time it can take for any undetected nits to hatch and produce more head lice.

You might need to use your fingernails to dislodge any nits from your child’s hair that escaped the comb and that are 15 mm or less from the scalp. Any further away than that and the nits will not hatch — they will be dead, or will have already hatched.

An added advantage of the hair conditioner-combing process is that it avoids the use of strong chemical pesticides on your child’s skin.

How effective is a chemical treatment of head lice?

There are chemicals you can buy at the chemist that kill head lice and are known to be safe for children aged more than 6 months, but there is no single chemical treatment that will work for everyone. Lice can develop resistance to the chemicals.

If you decide to use a chemical, it is important that you follow the instructions closely that come with it. You will need to repeat the chemical method within 7 days, as most treatments do not kill the eggs. The only way to test whether the treatment has worked is to use a nit comb and look for any live lice. If it has not worked, do not use the same chemical again — switch to another chemical, or use the comb and conditioner method.

What can be done to help prevent lice?

Prevention of head lice among young children is difficult. Lice move between them by head to head contact during play, and can survive for some hours on combs and brushes. One step to minimise the spread of head lice is to avoid sharing brushes and combs.

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Last reviewed: April 2021

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Treatment - Head lice

There are two main treatment options to remove head lice: mechanical removal and chemical removal. Head lice are only found on the human head or hair. Treating anything other than the human head does not eradicate head lice.

Read more on NSW Health website