Blood clot 10 weeks pregnant
Vaginal Bleeding and Blood Clots During Pregnancy
Written by Stephanie Watson
In this Article
- Bleeding in the First Trimester
- Bleeding in the Second and Third Trimesters
- What to Do If You Have Abnormal Bleeding During Pregnancy
Bleeding during pregnancy is common, especially during the first trimester, and usually it's no cause for alarm. But because bleeding can sometimes be a sign of something serious, it's important to know the possible causes, and get checked out by your doctor to make sure you and your baby are healthy.
Bleeding in the First Trimester
About 20% of women have some bleeding during the first 12 weeks of pregnancy. Possible causes of first trimester bleeding include:
Implantation bleeding. You may experience some normal spotting within the first six to 12 days after you conceive as the fertilized egg implants itself in the lining of the uterus. Some women don't realize they are pregnant because they mistake this bleeding for a light period. Usually the bleeding is very light and lasts from a few hours to a few days.
Miscarriage. Because miscarriage is most common during the first 12 weeks of pregnancy, it tends to be one of the biggest concerns with first trimester bleeding. However, first trimester bleeding does not necessarily mean that you’ve miscarried or will miscarry. In fact, if a heartbeat is seen on ultrasound, over 90% of women who experience first trimester vaginal bleeding will not miscarry.
Other symptoms of miscarriage are strong cramps in the lower abdomen and tissue passing through the vagina.
Ectopic pregnancy. In an ectopic pregnancy, the fertilized embryo implants outside of the uterus, usually in the fallopian tube. If the embryo keeps growing, it can cause the fallopian tube to burst, which can be life-threatening to the mother. Although ectopic pregnancy is potentially dangerous, it only occurs in about 2% of pregnancies.
Other symptoms of ectopic pregnancy are strong cramps or pain in the lower abdomen, and lightheadedness.
Molar pregnancy (also called gestational trophoblastic disease). This is a very rare condition in which abnormal tissue grows inside the uterus instead of a baby. In rare cases, the tissue is cancerous and can spread to other parts of the body.
Other symptoms of molar pregnancy are severe nausea and vomiting, and rapid enlargement of the uterus.
Additional causes of bleeding in early pregnancy include:
- Cervical changes. During pregnancy, extra blood flows to the cervix. Intercourse or a Pap test, which cause contact with the cervix, can trigger bleeding. This type of bleeding isn't cause for concern.
- Infection. Any infection of the cervix, vagina, or a sexually transmitted infection (such as chlamydia, gonorrhea, or herpes) can cause bleeding in the first trimester.
Bleeding in the Second and Third Trimesters
Abnormal bleeding in late pregnancy may be more serious because it can signal a problem with the mother or baby. Call your doctor as soon as possible if you experience any bleeding in your second or third trimester.
Possible causes of bleeding in late pregnancy include:
Placenta previa. This condition occurs when the placenta sits low in the uterus and partially or completely covers the opening of the birth canal. Placenta previa is very rare in the late third trimester, occurring in only one in 200 pregnancies. A bleeding placenta previa, which can be painless, is an emergency requiring immediate medical attention.
Placental abruption. In about 1% of pregnancies, the placenta detaches from the wall of the uterus before or during labor and blood pools between the placenta and uterus. Placental abruption can be very dangerous to both the mother and baby.
Other signs and symptoms of placental abruption are abdominal pain, clots from the vagina, tender uterus, and back pain.
Uterine rupture. In rare cases, a scar from a previous C-section can tear open during pregnancy. Uterine rupture can be life-threatening, and requires an emergency C-section.
Other symptoms of uterine rupture are pain and tenderness in the abdomen.
Vasa previa. In this very rare condition, the developing baby's blood vessels in the umbilical cord or placenta cross the opening to the birth canal. Vasa previa can be very dangerous to the baby because the blood vessels can tear open, causing the baby to bleed severely and lose oxygen.
Other signs of vasa previa include abnormal fetal heart rate and excessive bleeding.
Premature labor. Vaginal bleeding late in pregnancy may just be a sign that your body is getting ready to deliver. A few days or weeks before labor begins, the mucus plug that covers the opening of the uterus will pass out of the vagina, and it will usually have small amounts of blood in it (this is known as "bloody show"). If bleeding and symptoms of labor begin before the 37th week of pregnancy, contact your doctor right away because you might be in preterm labor.
Other symptoms of preterm labor include contractions, vaginal discharge, abdominal pressure, and ache in the lower back.
Additional causes of bleeding in late pregnancy are:
- Injury to the cervix or vagina
- Polyps
- Cancer
What to Do If You Have Abnormal Bleeding During Pregnancy
Because vaginal bleeding in any trimester can be a sign of a problem, call your doctor. Wear a pad so that you can keep track of how much you're bleeding, and record the type of blood (for example, pink, brown, or red; smooth or full of clots). Bring any tissue that passes through the vagina to your doctor for testing. Don't use a tampon or have sex while you are still bleeding.
Your doctor might recommend that you rest as much as you can and avoid exercise and travel.
You should expect to receive an ultrasound to identify what the underlying cause of your bleeding may be. Vaginal and abdominal ultrasounds are often performed together as part of a full evaluation.
Go to the emergency room or call 911 right away if you have any of the following symptoms, which could be signs of a miscarriage or other serious problem:
- Severe pain or intense cramps low in the abdomen
- Severe bleeding, with or without pain
- Discharge from the vagina that contains tissue
- Dizziness or fainting
- A fever of more than 100.4 or more degrees Fahrenheit and/or chills
Health & Pregnancy Guide
- Getting Pregnant
- First Trimester
- Second Trimester
- Third Trimester
- Labor and Delivery
- Pregnancy Complications
- All Guide Topics
Blood clots and pregnancy | March of Dimes
Anyone can develop a blood clot but pregnant women are at higher risk during pregnancy and after giving birth.
Blood clots can cause other health problems in pregnancy but there are ways to prevent and protect you and your baby.
It is important to know the signs of a blood clot and factors that may increase your risk for a blood clot.
Tell your health care provider if you or someone in your family has had problems with blood clots.
A blood clot (also called a thrombosis) is a mass or clump of blood that forms when blood changes from a liquid to a solid. The body normally makes blood clots to stop the bleeding after a scrape or cut. But sometimes blood clots can partly or completely block the flow of blood in a blood vessel, like a vein or artery.
Anyone can develop a blood clot, but you are at higher risk for a blood clot during pregnancy and up to 3 months after giving birth to your baby. Most women with blood clotting conditions have healthy pregnancies. But these conditions may cause problems for some pregnant women. In severe cases, they can cause death for both mom and baby. But testing and treatment can help protect and save both you and your baby.
If you’re pregnant or trying to get pregnant and have had problems with blood clots in the past, tell your health care provider at a preconception checkup (before pregnancy) or at your first prenatal care checkup.
If you or someone in your family like your parent, brother or sister has had problems with blood clots, talk to your provider. Blood clots may run in your family. You may also talk to your provider about getting a blood test to see if you have a thrombophilia. This is a health condition that increases your chances of making abnormal blood clots. Some pregnant women with thrombophilias need treatment with medicines called blood thinners. They stop clots from getting bigger and prevent new clots from forming.
Why are pregnant women at greater risk for blood clots?
Pregnant women are 5 times more likely to experience a blood clot compared to women who are not pregnant. This may be because:
- When you’re pregnant, your blood clots more easily to lessen blood loss during labor and delivery.
- In pregnant women, the blood may flow less to the legs later in pregnancy because the growing baby presses upon blood vessels around your pelvis.
- When you’re pregnant you may experience less movement or immobility (not moving a lot) like when you’re on bed rest or recovering from giving birth.
What are other reasons people may be at risk for having blood clots?
Certain things make you more likely than others to have a blood clot. These are called risk factors. Having a risk factor doesn’t mean for sure that you’ll have a blood clot. But it may increase your chances. Talk to your provider about what you can do to help reduce your risk.
Risk factors for blood clots include:
- Having certain health conditions, like a thrombophilia, high blood pressure, diabetes or being overweight or obese. A family history of blood clotting problems also increases your chances of blood clots.
- Taking certain medicines, like birth control pills or estrogen hormones. These medicines can increase the risk of clotting. If you’ve had problems with blood clots or thrombophilias or have a family history of these conditions, birth control pills may not be safe for you to use. Talk to your provider about other birth control options.
- Smoking. Smoking damages the lining of blood vessels, which can cause blood clots to form.
- Having surgery, like a cesarean section (also called c-section). A c-section is a surgery in which your baby is born through a cut that your doctor makes in your belly and uterus. The American College of Obstetricians and Gynecologists (ACOG) recommends that doctors help prevent blood clots in women during a c-section. This may include using compression devices that put pressure on your legs to help keep your blood flowing during the c-section.
- Being dehydrated. This means you don’t have enough water in your body. Dehydration causes blood vessels to narrow and your blood to thicken, which makes you more likely to have blood clots.
- Not moving around much. This may be because you’re on bed rest during pregnancy or recovering from surgery or an accident. Being still for long periods of time can lead to poor blood flow, which makes you more likely to have blood clots. Even sitting for long periods of time, like when traveling by car or plane for 4 hours or more, can increase your chances of having a blood clot.
- Having a baby. You’re more likely to have a blood clot in the first 6 weeks after birth than women who haven’t given birth recently.
What problems can blood clots cause during pregnancy?
If you have a blood clot or a kind of thrombophilia called antiphospholipid syndrome (also called APS), you may be more likely to have complications that can affect your health and your baby’s health, including:
Blood clots in the placenta. The placenta grows in your uterus (womb) and supplies the baby with food and oxygen through the umbilical cord. A blood clot in the placenta can stop blood flow to your baby and harm your baby.
Heart attack. This usually happens when a blood clot blocks blood and oxygen flow to the heart. Without blood and oxygen, the heart can’t pump blood well, and the affected heart muscle can die. A heart attack can lead to lasting heart damage or death.
Intauterine growth restriction (also called IUGR). This is when your baby grows poorly in the womb.
Miscarriage. A miscarriage is when a baby dies in the womb before 20 weeks of pregnancy.
Placental insufficiency. This is when the placenta doesn’t work as well as it should so your baby gets less food and oxygen.
Preeclampsia. This condition that usually happens after the 20th week of pregnancy or right after pregnancy. It’s when a pregnant woman has both protein in her urine and high blood pressure.
Premature birth. This is when your baby is born before 37 weeks of pregnancy.
Pulmonary embolism (also called PE). An embolism is a blood clot that moves from where it formed to another place in the body. When the clot moves to a lung, it’s a PE. PE can cause low oxygen levels in your blood and damage your body organs. It’s an emergency and a leading cause of death during pregnancy. Signs and symptoms of PE may include:
- Trouble breathing
- Fast or irregular heartbeat
- Chest pain
- Fainting
- Coughing up blood
Stillbirth. This is when a baby dies in the womb before birth but after 20 weeks of pregnancy.
Stroke. This happens when a blood clot blocks a blood vessel that brings blood to the brain, or when a blood vessel in the brain bursts open. Pregnancy and childbirth cause strokes in about 8 in 100,000 women. Stroke can cause lasting damage to the body or death.
Thrombosis. This happens when a blood clot forms in a blood vessel and blocks blood flow. It most often happens in the deep veins of the legs but can be in other places of the body:
- Cerebral vein thrombosis (also called CVT). This happens when a blood clot forms in a vein in the brain. CVT can lead to stroke. Signs and symptoms include headache, vision problems and seizures.
- Deep vein thrombosis (also called DVT). This happens when a blood clot forms in a vein deep in the body, usually in the lower leg or thigh. DVT can be diagnosed with ultrasound or other imaging tests. Signs and symptoms may include warmth and tenderness over the vein and pain, swelling or skin redness in the affected area.
Venous thromboembolism (also called VTE). This happens when a blood clot breaks off and travels through blood to vital organs, like the brain, lungs or heart. This condition includes DVT and PE. VTEs that block blood vessels in the brain or heart can cause stroke or heart attack.
How are these conditions treated?
Your provider may use tests like ultrasound or magnetic resonance imaging (also called MRI) to find out if you have a blot clot or clotting conditions. Ultrasound uses sound waves and a computer screen to make a picture of a baby in the womb. MRI uses magnets and computers to make a clear picture of the inside of the body. These tests are painless and safe for you and your baby.
If you’re pregnant and have a clotting condition, you may need to go for prenatal care checkups more often than women who don’t have these blood clot conditions. At these visits, your provider checks your blood pressure and can use other tests, like blood tests, to monitor your health.
Your provider also checks your baby’s health in the womb using tests like:
- Ultrasound to check your baby’s growth and development. She may use a special kind of ultrasound called Doppler to check your baby’s blood flow in the umbilical artery, a blood vessel in the umbilical cord. The umbilical cord connects your baby to the placenta. It carries food and oxygen from the placenta to the baby.
- Fetal heart rate monitoring (also called a nonstress test or NST). This test checks your baby’s heart rate in the womb and sees how the heart rate changes when your baby moves. Your provider uses this test to make sure your baby’s getting enough oxygen.
During pregnancy your provider may give you a blood thinner called heparin (low-molecular weight heparin or unfractionated heparin). If you have APS, your provider may instruct you to take heparin along with low-dose aspirin. Your provider also may refer you to a hematologist. This is a doctor who treats blood conditions.
After you give birth, your provider may continue to treat you with heparin. Or she may treat you with a blood thinner called warfarin. Warfarin is safe to take after pregnancy, even if you’re breastfeeding. Warfarin is not safe to take during pregnancy because it may cause birth defects.
Don’t take combined hormonal methods of birth control during the first 21-42 days after delivery. The risk of DVT is highest in the first 21 days.
How can I safely keep up with my prenatal care appointments during the COVID-19 pandemic?
During the coronavirus disease 2019 pandemic (COVID-19) your prenatal care visits may change. Ask your provider how he will monitor your health and do the tests you need while keeping you and your baby safe from COVID-19.
Providers are taking steps to prevent the spreading of COVID-19 by using telehealth or telemedicine. Telehealth or telemedicine are health visits where you talk to your provider by phone or by videocall, instead of going to his office. You will need either a phone, tablet or computer for a telehealth visit and in some cases you may need access to the internet. Let your provider know if you are unable to have telehealth visits due to lack equipment or any other reason. Ask any questions you may have about keeping up with your ultrasounds and other tests while avoiding getting COVID-19.
What can I do to reduce my risk of blood clots?
- Know the signs and symptoms of a blood clot. On an affected limb like a leg or arm, you may notice swelling, pain or tenderness that was not caused by an injury, warm skin when you touch it or redness and discoloration. Contact your provider if you experience any of these symptoms.
- Talk to your provider about your risk. If you or a family member like a parent, brother or sister have had blood clots before, tell your provider.
- Move or stretch on long trips. If you sit for more than 4 hours on a trip, try to move your legs often. If you can walk around, you may do so. If you can’t, you may try seated leg stretches like extending your legs straight out and moving your ankles to move your toes toward and away from you. You may also pull your knee to your chest and hold it there with your hands for 15 seconds.
- Follow other travel tips for reducing risk of blood clots. These include drinking lots of fluids like water, wearing loose-fitted clothing or wearing special stockings that compress your legs below the knee. Talk to your provider before trying these stockings.
- Follow your provider’s instructions during pregnancy and after giving birth. Your provider may give you medications like blood thinners or ask you to come in for additional prenatal care checkups.
Last reviewed September 2022
More information
- Shane Foundation
- Stop The Clot, Spread the Word™ campaign
Thrombophlebitis during pregnancy: pay attention!
Pregnancy is a happy time, which is also associated with anxiety. In particular, this is the possible development of varicose veins and its complications - thrombophlebitis. Unfortunately, the body of the expectant mother is exposed to various factors that contribute to the formation of blood clots in the veins. Why is thrombophlebitis dangerous in pregnant women and how to treat it? Let's try to figure it out.
What is thrombophlebitis?
Thrombophlebitis is an inflammatory process in the veins, which is accompanied by the formation of blood clots, that is, blood clots themselves. Clots begin to grow near the vein stack and gradually spread throughout the vessel. If the vein is of small diameter, an inflow of the main trunk, then it can be completely closed by a thrombus, but this does not pose a serious threat to health and life. If clots form in large veins on the legs, then this is dangerous due to their spread into the system of the inferior vena cava or the separation of a blood clot. nine0003
Thrombophlebitis develops against the background of slow venous blood flow, which occurs with varicose veins. If an injury to the venous wall is added to this (and a stretched vein is also damage), then this is an additional factor that contributes to the onset of blood clots.
Thrombophlebitis during pregnancy
The development of thrombophlebitis during pregnancy is accelerated by several factors at once:
- increase in body weight and, accordingly, an increase in the load on the veins of the legs; nine0018
- increase in blood volume, which can lead to a general slowdown in blood flow and distension of the vein
- changes in the composition of the blood, which may increase its clotting;
- hormonal changes in the body that affect the blood coagulation system. In particular, an increase in the level of the "pregnancy hormone" progesterone also increases the risk of blood clots.
In addition, pregnant women have an increased risk of developing thrombosis. This is also the formation of blood clots, but not in superficial, but in deep veins. This pathology is not associated with varicose veins, and other factors contribute to its development. In particular, the age of the future mother is over 35 years old, numerous previous pregnancies, long-term use of oral contraceptives before pregnancy, a number of past diseases (for example, collagenoses), prolonged bed rest, vein injuries, including as a result of numerous injections into them. nine0003
Please note: thrombophlebitis during pregnancy and thrombosis during pregnancy are different diseases that affect the superficial (thrombophlebitis) or deep veins of the legs. The symptoms of thrombophlebitis appear brighter, so it is easier to notice it in time and start treating it. Thrombosis symptoms may not be so pronounced, erased, so the disease is especially dangerous for expectant mothers.
How is thrombophlebitis manifested in pregnant women
The symptoms of thrombophlebitis in pregnant women do not differ from the symptoms of the disease in everyone else. In the area of the affected vein, there is redness, thickening of the skin, the surface of the leg may feel hot to the touch. Swelling of the leg may begin, as well as pain. nine0003
Pain in thrombophlebitis increases when walking and subsides at rest. However, sometimes the pain can be very severe, so that the patient cannot step on the foot. Women often complain of general poor health.
All this is a consequence of stagnation of blood in the veins and the gradual formation of a blood clot that closes the lumen of the vessel.
Thrombophlebitis during pregnancy: treatment and prevention
According to experts, pregnancy increases all the risks that exist for the body of a particular woman. And including the increased risk of developing thrombophlebitis. That is why if a pregnant woman already has a diagnosis of varicose veins, she should very carefully approach the issue of preventing thrombophlebitis. That is, constantly wear compression stockings prescribed and selected on the recommendation of a doctor. nine0003
If the expectant mother noticed the first signs of thrombophlebitis on her legs - redness, induration in the region of the vein, then she needs to immediately contact a specialist. If a woman has a compression stocking or an elastic bandage, then before visiting the doctor, her leg can be bandaged or put on knitwear on her own. But vein examination (ultrasound, duplex scanning) should be done as soon as possible.
Treatment of thrombophlebitis during pregnancy includes the mandatory wearing of compression stockings, which ensures normal blood flow in the vein, as well as taking heparin drugs that reduce blood viscosity. nine0003
Postpartum thrombophlebitis
Thrombophlebitis can develop in a woman not only during childbirth, but also after them. It usually starts 2-3 weeks after childbirth and can spread from inflamed uterine veins. Often a young mother complains not only of pain, but of chills, general deterioration, and fever. However, these are not symptoms of a cold, but of thrombophlebitis, which cannot be ignored.
Thrombophlebitis is undoubtedly one of the most serious complications of varicose veins. However, knowing about its symptoms, the disease can be detected in time and measures taken. Be attentive to yourself, and this will help you maintain the beauty and health of your legs for a long time! nine0003
Thrombogenic risk factors in pregnant women.
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Minsk Clinical Consultative and Diagnostic Center Book online If a woman has a history of recurrent miscarriage or fetal loss in late pregnancy, second toxicosis half pregnancy, intrauterine growth retardation, placental abruption or placental infarction, she should be tested for thrombophilia. Hyperhomocysteinemia, which sometimes develops under the influence of hereditary genetic polymorphism, is associated with late toxicosis and is involved in the development of infarcts and placental abruption. Inflammation of the endothelial lining of blood vessels associated with elevated levels of homocysteine causes an increased risk of both venous and arterial thrombosis. Hyperhomocysteinemia can be caused by the presence in the body of altered forms of the enzyme methylenetetrahydrofolate reductase (MTHFR), which is normally involved in the conversion of homocysteine to methionine. nine0003 Hereditary polymorphism of factor Leiden (V), which has a strong predisposition to thrombosis, occurs with an increased frequency in women with recurrent miscarriage. Among patients with recurrent miscarriage, abnormal forms of factor V Leiden are most common in women who have miscarriages in the second trimester of pregnancy. Hyperhomocysteinemia itself does not have a significant association with early fetal loss, suggesting that folic acid deficiency and MTHFR polymorphism may act through additional, as yet unknown factors. Elevated levels of homocysteine are also detected during pregnancies complicated by preeclampsia, and this increase persists after childbirth. nine0003 Other causes of placental thrombosis. Pregnancy may contribute to the manifestation of a genetic defect, as it develops the following features: The risk of thrombosis in inherited forms of thrombophilia can be reduced by the use of small doses of aspirin, heparin, folic acid, intravenous immunoglobulin G, or hematogenous factor concentrates. For carriers of inherited thrombophilia with recurrent adverse pregnancy outcomes, two prophylactic treatment options deserve attention: administration of low molecular weight heparin (enoxaparin) to women with recurrent late fetal loss and folic acid treatment for severe toxicosis of the 2nd half of pregnancy. nine0003 In all pregnant and non-pregnant individuals, folic acid intake significantly reduces homocysteine levels. Efficiency is high in cases where pre-treatment homocysteine levels were highest and lowest if homocysteine levels were relatively low. A decrease in homocysteine levels has been observed with the use of folic acid at a dose of 0.5 mg to 5 mg per day in combination with vitamin B6. There is a high probability of thromboembolic complications and in the presence of cardiovascular diseases, overweight, anemia, late toxicosis. The risk of thrombosis also increases in women in the age group after 40 years, in the presence of malignant tumors, a sedentary lifestyle. Prolonged, prolonged labor, caesarean section also predispose to complications. The group of very high risk for the development of thrombosis, including in the postpartum period, includes women with varicose veins of the lower extremities. nine0003 Causes of thrombosis First of all, the development of postpartum thrombosis is associated with changes in the blood coagulation system. During natural childbirth or caesarean section, blood is lost. The volume of blood loss can be different - from minimal (physiological) to significant (pathological), which depends on the specific situation. In any case, the body seeks to stop further blood flow, producing a large number of factors that increase blood coagulation by forming clots-plugs in the lumen of blood vessels. And the more blood loss, the more active these processes. In addition, when the placenta passes or due to mechanical tissue damage during the operation, the vessel wall is also damaged, special proteins and enzymes of the endothelium (the inner lining of the vessel) are released into the blood, which is also important for shifting processes towards increased blood coagulation. nine0003 To reduce the risk of venous thromboembolic complications during pregnancy, the use of low molecular weight heparins (LMWH) in prophylactic and intermediate doses in the form of subcutaneous injections is recommended. However, at present, the decision to prescribe LMWH to pregnant women is made only on the basis of a thrombotic history or if a particular thrombophilia is detected (factor V Leiden mutations, prothrombin mutations, antithrombin deficiency, carriage of antiphospholipid antibodies, etc.). These indications for the appointment of LMWH are subjective, since they are not based on accurate laboratory data measuring excessive (thrombotic) activation of blood coagulation at different stages of pregnancy. Accordingly, the use of these indications leads to unreasonably widespread use of heparins during pregnancy. nine0003 Congenital thrombophilia (a condition of increased blood clotting), caesarean section, advanced age of the woman in labor and overweight increase the likelihood of blood clots during pregnancy. If a woman has previously given birth three or more times or has multiple pregnancies (twins or more), the risk of thrombosis also increases. Additional risk factors for blood clots are: hypertension, cardiovascular disease and diabetes; use of oral contraceptives before pregnancy; dehydration. nine0003 It is important to note that the risk of blood clots persists for up to two months after delivery. The treatment of thrombosis is a complex process that must necessarily take place under the supervision of a physician. Therefore, in the presence of risk factors, thrombosis prophylaxis is recommended. Prevention can be non-drug and drug. The doctor determines the degree of risk for each patient - low, moderate, high. After that, a method of prevention is selected. As a rule, one non-drug prophylaxis is not enough for people with an increased risk of developing thrombosis, therefore, drug prophylaxis is carried out along with it. In this case, special drugs are used that prevent the formation of blood clots. nine0003 Antiphospholipid syndrome (APS) is the cause of many obstetric complications such as fetal loss syndrome, HELLP syndrome, preterm birth. The high risk of adverse obstetric outcomes in APS necessitates pregnancy planning and the selection of adequate therapy for a pregnant woman with this pathology. Today, APS is one of the urgent problems in obstetric practice. Clinical manifestations of APS in obstetrics are fetal loss syndrome, intrauterine growth retardation, HELLP syndrome, oligohydramnios, fetoplacental insufficiency, preterm birth, preeclampsia (preeclampsia and eclampsia). Fetal loss syndrome is currently considered as a specific marker of APS. Termination of pregnancy in APS can occur at any stage of pregnancy, and very often spontaneous miscarriage is the only symptom to suspect APS in a patient. nine0003 The high risk of adverse obstetric outcomes in APS dictates the need for pregnancy planning in these patients, careful selection of drug therapy and constant monitoring of the mother and fetus. At the stage of planning pregnancy in a patient with APS, it is necessary to exclude concomitant risk factors for thrombosis. The range of preventive measures includes correction of excess weight, treatment of concomitant arterial hypertension, correction of lipid disorders, smoking cessation, as well as the use of compression stockings for post-thrombophlebitic syndrome. nine0003 Pregnant women with APS from the moment of conception are prescribed low doses of ASA (50-100 mg per day, but not more than 150 mg per day) and low molecular weight heparins until the moment of delivery. Cancel low molecular weight heparins 12-24 hours before delivery. Treatment with heparins is resumed 12 hours after delivery for a period of at least 4-6 weeks. Timely diagnosis and adequate therapy of APS in pregnant women, careful monitoring of hemostasis system parameters, regular monitoring of the fetal condition, joint management of pregnancy by an obstetrician-gynecologist and related specialists can improve perinatal outcomes. +375 17 355 94 50 (Hor. ) +375 29 238 00 90 (mobile MTS) +375 44 550 00 90 (mobile A1) You are here: