Bladder infection or pregnancy
UTIs during pregnancy are common and treatable | Your Pregnancy Matters
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Your Pregnancy Matters
September 20, 2021
Your Pregnancy Matters
Robyn Horsager-Boehrer, M. D. Obstetrics and Gynecology
As you adjust to new changes in your body during pregnancy, it can be easy to overlook symptoms of everyday health conditions, such as urinary tract infections (UTIs). UTIs are equally common in pregnant and non-pregnant patients and usually require medication to clear the infection.
But if left untreated during pregnancy, a UTI can progress to s serious infection that can lead to preterm labor, premature delivery, or even fetal loss.
UTIs occur when bacteria enter and grow in the urinary tract.
During pregnancy, your bladder – which is in the lower part of your urinary tract – is less likely to empty entirely when you urinate, thanks to pressure from your expanding uterus and an increase in hormones that relax the muscles in your uterus. The longer urine stays in your body, the higher the chances that you’ll grow too much bacteria.
We watch for three types of UTIs during pregnancy:
- Asymptomatic: Approximately 7% of pregnant women may have a UTI that doesn’t cause symptoms. An untreated asymptomatic infection has a 25% chance of advancing to the next level of UTI – your bladder and then your kidney.
- Cystitis: Localized to the bladder, this infection will cause symptoms typically associated with UTIs, such as frequent but small amounts of urine, painful urination, and strong urges to urinate immediately.
- Pyelonephritis: This kidney infection can lead to serious issues such as septic shock, anemia, excess lung fluid, and pre-term labor.
It typically includes the symptoms of cystitis, plus nausea, fever, chills, and pain in your lower back and sides.
Because UTIs are prevalent during pregnancy, we request a urine sample to conduct a culture test as part of your prenatal care. The test looks for specific types of bacteria in your urine that can cause an infection.
We will likely test your urine multiple times throughout your pregnancy. But don’t assume we’re looking for a UTI every time; this is a common misconception. It’s important to talk with your doctor if you experience UTI symptoms to make sure you get the right test. The earlier we diagnose a UTI, the sooner we can treat you and prevent a more dangerous condition.
UTI treatment: What to expect
UTI treatments during pregnancy are safe and easy, usually involving a short course (3-7 days) of oral antibiotics. There are two exceptions:
- If you continue to have UTIs after we treat the first one, we may recommend suppressive therapy.
You will take a lower dose of antibiotics every day of your pregnancy instead of larger doses for just a few days. - If you have pyelonephritis (kidney infection), you will need to receive antibiotics through an IV at a hospital.
For most patients, receiving antibiotic treatment is much safer than risking a kidney infection. We will discuss all your health conditions and pregnancy symptoms to determine the best type of antibiotic for you, depending on what will work effectively against the bacteria in your urine.
Not all urine tests are the same
In the third trimester, we’ll likely test your urine for the presence of protein or glucose, which can indicate high blood pressure or gestational diabetes. Around this time, we also test urine for sexually transmittable diseases such as chlamydia and gonorrhea, which can be transferred to your baby.
Neither of these tests will tell us whether you have a UTI. If you’re experiencing UTI symptoms, please tell us so we can perform the appropriate test and begin treatment.
What increases or reduces risk of UTIs during pregnancy?
Women who have or carry the trait for sickle cell disease are at increased risk for UTIs. We test these patients monthly to ensure we detect an infection as soon as possible.
If you have diabetes, you’re also at a higher risk. We might not test you as frequently, but we will consistently look for symptoms. Both conditions make it harder for the body to fight infections.
Just as when you’re not pregnant, you can take specific actions to lower your chances of getting a UTI, such as:
- Wiping front to back in the bathroom
- Urinating before and after sex
- Wearing cotton underwear
- Avoiding tight and wet clothing
- Drinking more water
Prepare for possible postpartum UTIs
In some cases, the risks of developing a UTI increase after you give birth.
Patients who have a C-section or receive an epidural during labor have a catheter inserted into their bladder.
This ensures a safer delivery by keeping your bladder empty. But a catheter increases your risk of infection the longer it stays in your body, and its placement provides the perfect track for bacteria to enter your bladder.
To decrease your UTI risk, our goal is to remove your catheter no more than six to eight hours after surgery and even sooner after an epidural. An infection can take days to appear, so watch for symptoms after you leave the hospital and tell your doctor right away if you experience them. We don’t perform routine UTI tests after delivery, so it’s important to alert us to abnormal pain or discomfort.
Related reading: Tips to prevent involuntary urine leakage (incontinence) during and after pregnancy
With so many new tasks to complete and emotions to experience after bringing your newborn home, it can feel overwhelming to keep track of one more thing – but your health remains a priority after the birth of your baby. The more you tell us about how you feel, the more we can do to help you stay healthy.
To visit with an Ob/Gyn, call 214-645-8300 or request an appointment online.
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Urinary Tract Infection During Pregnancy: Symptoms & Prevention
A urinary tract infection (UTI), also called bladder infection, is a bacterial inflammation in the urinary tract. Pregnant women are at increased risk for UTIs starting in week 6 through week 24 because of changes in the urinary tract. The uterus sits directly on top of the bladder. As the uterus grows, its increased weight can block the drainage of urine from the bladder, causing a urinary tract infection during pregnancy.
What are the signs and symptoms of UTIs?
If you have a urinary tract infection, you may experience one or more of the following symptoms:
- Pain or burning (discomfort) when urinating
- The need to urinate more often than usual
- A feeling of urgency when you urinate
- Blood or mucus in the urine
- Cramps or pain in the lower abdomen
- Pain during sexual intercourse
- Chills, fever, sweats, leaking of urine (incontinence)
- Waking up from sleep to urinate
- Change in the amount of urine, either more or less
- Urine that looks cloudy, smells foul or unusually strong
- Pain, pressure, or tenderness in the area of the bladder
- When bacteria spreads to the kidneys you may experience back pain, chills, fever, nausea, and vomiting.
How will a UTI affect my baby?
If the UTI goes untreated, it may lead to a kidney infection. Kidney infections may cause early labor and low birth weight. If your doctor treats a urinary tract infection early and properly, the UTI will not cause harm to your baby.
How do I know if I have a UTI?
A urinalysis and a urine culture can detect a urinary tract infection throughout pregnancy.
What treatment options are available?
UTIs can be safely treated with antibiotics during pregnancy. Urinary tract infections are most commonly treated by antibiotics. Doctors usually prescribe a 3-7 day course of antibiotics that is safe for you and the baby. Call your doctor if you have fever, chills, lower stomach pains, nausea, vomiting, contractions, or if after taking medicine for three days, you still have a burning feeling when you urinate.
How can I prevent a bladder infection?
You may do everything right and still experience a urinary tract infection during pregnancy, but you can reduce the likelihood by doing the following:
- Drink 6-8 glasses of water each day and unsweetened cranberry juice regularly.
- Eliminate refined foods, fruit juices, caffeine, alcohol, and sugar.
- Take Vitamin C (250 to 500 mg), Beta-carotene (25,000 to 50,000 IU per day) and Zinc (30-50 mg per day) to help fight infection.
- Develop a habit of urinating as soon as the need is felt and empty your bladder completely when you urinate.
- Urinate before and after intercourse.
- Avoid intercourse while you are being treated for a UTI.
- After urinating, blot dry (do not rub), and keep your genital area clean. Make sure you wipe from the front toward the back.
- Avoid using strong soaps, douches, antiseptic creams, feminine hygiene sprays, and powders.
- Change underwear and pantyhose every day.
- Avoid wearing tight-fitting pants.
- Wear all-cotton or cotton-crotch underwear and pantyhose.
- Don’t soak in the bathtub longer than 30 minutes or more than twice a day.
Want to Know More?
- 7 Common Discomforts of Pregnancy
- How Your Body Changes During Pregnancy
- Pregnancy Nutrition
- Exercise During Pregnancy
Compiled using information from the following sources:
1.
American Academy of Family Physicians
https://www.aafp.org/
2. William’s Obstetrics Twenty-Second Ed. Cunningham, F. Gary, et al, Ch. 48.
Urinary tract infections vs pregnancy: treatment and prevention
Summary. Urinary tract infections are one of the most common complications in pregnant women, which can lead to serious consequences not only for the expectant mother, but also for the child. When managing pregnant women with diseases of the urinary system, it is extremely important to choose the right and, most importantly, safe therapeutic tactics. What drugs are safe during pregnancy? What obstetric and therapeutic tactics are most effective for kidney diseases in pregnant women? What diagnostic methods are best used for asymptomatic bacteriuria, acute cystitis and pyelonephritis? Professor 9 spoke about this in her speech0003 Olga Grishchenko , Head of the Department of Perinatology, Obstetrics and Gynecology of the Kharkov Medical Academy of Postgraduate Education during the training workshop for gynecologists "Actual Guidelines of Gynecology, Reproductology, Obstetrics", held on March 29, 2019 in Kharkov.
The event was organized by the MedExpert Group of Companies together with the National Medical University named after A.A. Bogomolets and National Medical Academy of Postgraduate Education named after P.L. Shupyk. nine0007
Urgency of the problem
Urinary tract infections (UTIs) are the most common bacterial infections in outpatient practice, they take the 2nd place, second only to respiratory tract infections. According to statistics, 50% of women in the world have an episode of UTI at least once in their lives, of which 25–40% experience a relapse of the disease within 6–12 months. Every year, about 10% of women develop acute cystitis, and pyelonephritis remains the leading cause of hospitalization during pregnancy for non-obstetric indications. nine0007
In the presence of UTI in pregnant women, the risk of preterm labor and rupture of amniotic fluid, chorioamnionitis increases, premature or functionally immature children are born, and the level of perinatal mortality increases.
In the structure of UTI, asymptomatic bacteriuria is observed in 4-9.5% of pregnant women, acute pyelonephritis - in 12-25%, chronic pyelonephritis - in 33%, glomerulonephritis, urolithiasis - in 0.1-0.2%.
Risk factors and pregnancy
As a rule, infections, self-medication or improper treatment, asymptomatic bacteriuria, frequent UTIs in combination with inflammatory diseases (colpitis), lifestyle and nutrition can affect the occurrence of pathology of the urinary system. nine0007
Pregnant women have an increased risk of diseases of the urogenital tract. A high level of progesterone leads to the development of hypotension, hypokinesia, dyskinesia of the ureters and pyelocaliceal system. In turn, the uterus compresses the ureter, high intra-abdominal pressure occurs, especially in primiparas. During pregnancy, the renal pelvis enlarges, the growing uterus squeezes the ureter more and more, the outflow of urine from the kidneys becomes difficult, the urine stagnates, bacteria multiply in it, and inflammation easily occurs.
nine0007
Infectious agents can enter the bladder by ascending (with inflammatory diseases of the urethra), descending (most often with tuberculous kidney damage), hematogenous (if there is a purulent focus in other parts of the body) and lymphogenic (with diseases of the genital organs) by.
Classification of UTIs in pregnant women
UTIs in pregnant women include asymptomatic bacteriuria, lower urinary tract infections (acute and recurrent cystitis) and upper urinary tract infections (acute pyelonephritis, chronic pyelonephritis in remission, exacerbation, latent course). nine0007
Cystitis in pregnancy: course, diagnosis
Cystitis is an inflammation of the bladder wall, one of the most common urological diseases, as a rule, its cause is an infection. Symptoms of cystitis in women are manifested in the form of frequent urination, cramps and pain when urinating, pulling sensations in the lower abdomen, weakness, fatigue, irritability, blood in the urine, cloudy urine, pus or yellow spots on the underwear.
Normally, urination is not accompanied by pain. In women, painful urination can be caused by diseases of the bladder, urethra, or vagina. So, pain in the bladder, as a rule, is felt in the area of the womb, it can increase during urination or, conversely, decrease when the bladder is empty. Urethral pain associated with urination is felt by the patient directly in the urethra and is usually aggravated by urination. Urine entering the vaginal opening can cause pain if it is inflamed. Inflammation of the urethra is most often characterized by a bacterial nature and requires additional examination and treatment. nine0007
Primary diagnosis of cystitis involves an examination by specialized specialists (urologist, nephrologist, gynecologist), as well as taking an anamnesis and establishing possible causes of the disease (hypothermia, unprotected intercourse, taking medications, the presence of concomitant diseases).
Laboratory tests include a urinalysis for Nechiporenko cultures (helps identify the pathogen), a general urinalysis (allows you to identify erythrocytes, leukocytes, protein in the urine; the urine itself may be cloudy with an admixture of blood or pus), a general blood test (allows you to identify a picture inflammatory process, it is possible to increase the erythrocyte sedimentation rate (ESR), leukocytosis).
Among instrumental methods, ultrasound examination (ultrasound) of the bladder, ureteroscopy and cystoscopy (in case of violation of the passage of urine) are used. nine0007
Asymptomatic bacteriuria during pregnancy
Asymptomatic bacteriuria during pregnancy is dangerous for both mother and fetus, against its background, 25% of women develop acute pyelonephritis. According to the World Health Organization, about 8% of women report asymptomatic bacteriuria, 15-57% of women with untreated asymptomatic bacteriuria develop symptoms of a UTI (acute cystitis or pyelonephritis). Therapy of this disease during pregnancy reduces the risk of developing acute UTIs, preterm birth, and low birth weight. nine0007
Diagnosis of asymptomatic bacteriuria can be established by detecting 10 5 CFU/ml of one bacterial strain or 10 2 CFU/ml of uropathogen Escherichia coli field of view in the absence of clinical manifestations of UTI.
It should be remembered that the risk of this pathology is most real from the 9th to the 17th week of pregnancy.
The only reliable method for diagnosing asymptomatic bacteriuria is the method of urine culture. nine0007
In accordance with Ukrainian and international guidelines for asymptomatic bacteriuria, oral antibiotic therapy with a single dose of fosfomycin trometamol is recommended.
Pyelonephritis: diagnosis
Pyelonephritis is an infectious and inflammatory disease of the kidneys of bacterial etiology with a primary and predominant lesion of the interstitium and tubular apparatus. The incidence of pyelonephritis during pregnancy reaches 33%, mortality - 3.5%, maternal mortality from kidney disease in the structure of extragenital pathology is 8-10%, the incidence of gestational pyelonephritis is 11.5%. nine0007
Primary pyelonephritis in pregnant women is difficult to treat, may be accompanied by fever, chills, nausea, vomiting, pain in the lumbar region, the appearance of pyuria, bacteriuria. As a rule, the right kidney is affected more often than the left one, with expansion of the pelvicalyceal system (according to ultrasound).
In acute pyelonephritis, the mandatory research methods are a general urinalysis (in 2 portions) 1 time in 7 days, a Nechiporenko urinalysis, a general and biochemical blood test, a bacteriological urinalysis, ultrasound of the kidneys and bladder, daily proteinuria, a biochemical blood test , blood pressure monitoring, urologist consultation. Additional research methods - computed tomography without contrast or excretory urogram, nuclear magnetic resonance imaging - are carried out exclusively for strict, sometimes vital, indications. nine0007
It should be remembered that dysuria in primary acute cystitis with a body temperature of 38 ° C and chills may indicate acute ascending pyelonephritis. A sharp dysuric syndrome is characteristic of the associated cystitis during exacerbation of chronic pyelonephritis. Urinary syndrome (proteinuria, leukocyturia, hematuria, etc.) may periodically disappear with a unilateral process and ureter occlusion; therefore, serial urine tests are necessary.
The degree of leukocyturia does not always correspond to the severity of the inflammatory process. A single urine culture gives at least 20% false positive results. Bacteriuria appears and can be detected 2 days earlier than pyuria. nine0007
Choice of drugs for the treatment of pregnant women with UTIs
There are certain requirements for antibiotics for the treatment of UTIs in pregnant women. In particular, they must be effective against most pathogenic pathogens, have the ability to create a high concentration in organs - foci of infection, have a long half-life sufficient to maintain a high concentration of the antibiotic in the blood, not have toxic and allergic effects, be well tolerated by patients, be harmless to mother and fetus. nine0007
It has been shown that for the treatment of pregnant women with acute cystitis, asymptomatic bacteriuria, acute pyelonephritis, it is advisable to use antibacterial uroseptics. In particular, fosfomycin trometamol has a bactericidal effect associated with blocking the bacterial enzyme involved in the synthesis of the cell wall, as well as an anti-adhesive effect (destroys the fimbria of Escherichia coli, preventing it from fixing on the wall of the urothelium and promoting leaching from the urinary tract).
After a single dose of the drug, the therapeutic concentration is observed for 48 hours (this is enough to sterilize urine and recover). nine0007
An alternative to antibiotics are phytoneering preparations with anti-adhesive and antibacterial activity, as well as anti-inflammatory, antispasmodic, nephroprotective properties.
Organization of care for pregnant women with UTI and prevention
Delivery of pregnant women with UTI (without obstetric pathology) is carried out through the natural birth canal, taking into account the obstetric situation.
There are degrees of risk of pyelonephritis:
- I degree - uncomplicated pyelonephritis that occurred during pregnancy; nine0087
- II degree - chronic uncomplicated pyelonephritis, noted before pregnancy;
- III degree - pyelonephritis with hypertension, azotemia, pyelonephritis of a single kidney.
They must be taken into account when managing pregnant women.
So, at I-II degree of risk, pregnancy can be prolonged, but at III degree (creatinine> 265 μmol / l, glomerular filtration rate < 30 ml / min), pregnancy should be terminated.
Prevention of UTIs in pregnant women should include sanitation of the vagina in case of violation of its microflora and other sources of infection (teeth, pharynx, etc.), normalization of bowel function, optimal water regime. nine0007
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Marina Kolesnik,
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