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HCG Levels in Pregnancy & hCG Levels Chart by Week

Human chorionic gonadotropin, or hCG for short, is often referred to as “the pregnancy hormone” because it’s present in large quantities during pregnancy. And it is, after all, the hormone that many at-home pregnancy tests are designed to detect! Find out more about what hCG is, when it’s detectable by at-home pregnancy tests, and what the typical hCG levels are for each of the early weeks of pregnancy.

What Is hCG and When Does Your Body Start Producing It?

Human chorionic gonadotropin (hCG) is known as the pregnancy hormone, as your body produces it in large amounts when you’re pregnant.

Although you can have low levels of hCG in your body at any time, the levels of this hormone tend to rise sharply early on in your pregnancy for two reasons:

1. About 10 days after conception, the fertilized egg attaches to the lining of your uterus and your body starts to make hCG. Over the next week or so, hCG levels will increase.

2. At about 4 weeks pregnant, the egg—now called an embryo—implants further into the uterus and begins to produce even more hCG, which triggers increased productions of other hormones like estrogen and progesterone.

Together, these hormones help build the lining of the uterus and send signals to the ovaries to stop releasing eggs, ultimately stopping your period.

During these early weeks of pregnancy, you may not show any outward signs of being pregnant and you may not even suspect that you’re pregnant! You may, however, experience implantation bleeding when the fertilized egg attaches to the lining of the uterus (as described above). This is normal and may resemble spotting or a light period.

When Can Pregnancy Tests Detect hCG?

Home pregnancy tests often work by detecting hCG in your urine. All of these over-the-counter pregnancy tests work a little differently, so check the instructions in or on the box. Keep in mind that hCG levels increase over time, so at-home tests are more accurate as your pregnancy progresses. Therefore, a home-pregnancy test that’s taken too early might not detect low levels of hCG and could produce a false negative, meaning the result is negative when you’re actually pregnant. If you’re wondering when to take an at-home pregnancy test, try one of the following timelines:

• You might try taking a pregnancy test about three to four weeks after the first day of your last period, as this is when the levels of hCG in your urine will have increased enough to be detectable.

• You could wait until around the time you miss your next period, which could be the initial clue that you may be pregnant anyway! By then, the levels of hCG are detectable.

A blood test is the most accurate way to detect hCG levels, because more of the pregnancy hormone is present in the blood than in the urine. Plus, blood tests need less of the hCG hormone to detect a pregnancy, as explained below:

• Blood tests. Pregnancy blood tests can detect hCG hormone levels as low as 5 to 10 mIU/mL.

• Urine tests. At-home urine tests require higher levels of hCG to detect a pregnancy, typically at least 20 mIU/mL.

If your home pregnancy test is positive, your healthcare provider may offer a blood test to check your hCG levels. The results can help your provider confirm your pregnancy and determine how far along you are.

If you’ve just found out you’re pregnant, you can get an estimate of your due date with our Due Date Calculator using either the date of conception or the date of the first day of your last menstrual period!

hCG Levels Chart by Week

The week-by-week chart below will give you an idea of how your hCG levels may rise during the first trimester, and then dip slightly during the second trimester. Keep in mind that, if you want your hCG blood test results explained in more detail, your healthcare provider is the best person to ask.

What Does It Mean if You Have High or Low hCG Levels?

It’s important to remember that every pregnancy is different, and you may have lower or higher levels of hCG hormone than what’s indicated in the week-by-week chart above. Most likely, there’s no cause for concern, but your healthcare provider will help you understand what these levels mean.

Low Levels of hCG

Low levels of hCG are normal for non-pregnant women and men. Normally, hCG levels would be less than 5 mIU/mL and less than 2 mIU/mL, respectively, for these groups. If you’re pregnant and experience low hCG levels, it’s important to look at your entire pregnancy as a whole. Your healthcare provider will consider all the factors of your pregnancy to determine why you might be experiencing lower-than-normal levels of hCG. If your provider suspects anything like an ectopic pregnancy, they may perform additional tests to rule it out.

High Levels of hCG

Likewise, high levels of the hCG hormone might not indicate anything out of the ordinary. However, a higher-than-normal level of hCG may be a sign that you’re having twins or triplets! Again, your healthcare provider will work with you to determine an appropriate course of action, if any is needed. Lower- or higher-than-normal levels of the hCG hormone during your pregnancy might not indicate anything unusual. However, it’s always a good idea to follow up with your healthcare provider as a precaution, regardless of any questions or concerns you have. Read more about other pregnancy symptoms not to ignore.

The Bottom Line

The hCG hormone plays an important role in your pregnancy, and the changing levels of this hormone are just one of many transformations your body will experience as your baby develops. Although hormonal changes can make you feel a little off from time to time during your pregnancy, try to take these as reassurance that your baby is growing, and you’re getting closer and closer to the day you finally get to meet them. In the meantime, prepare for your baby’s arrival and get rewards on all your diapers and wipes purchases with the Pampers Club app! Ready to share your pregnancy news with friends and family? Get creative pregnancy announcement ideas in the video below!

HCG norms by weeks of pregnancy

Content

1. Table of average hCG norms
2. Table of average hCG norms for carrying twins
3. Table of average hCG values ​​after IVF with engrafted twins
4. Guidelines for free β-hCG subunit
5. Norm РАРР-А
6. What if I am at high risk?
7. How to confirm or deny the results of screening?
8. The doctor says I need an abortion. What to do?

One of the main tests during pregnancy is the study of the level of pregnancy hormone - hCG or human chorionic gonadotropin. If future mothers want to know if the hormone level is normal, we made a summary table of values ​​

Table of average hCG norms:

Gestation period	HCG in honey/ml	HCG in mIU/ml	HCG in ng/ml
1-2 weeks	25-156	5-25 (doubtful result)	-
2-3 weeks	101-4870	5-25 (doubtful result)	-
3-4 weeks	1100 – 31500	25-156	-
4-5 weeks	2560 – 82300	101-4870	-
5-6 weeks	23100 – 151000	1110 -31500	-
6-7 weeks	27300 – 233000	2560 -82300	-
7-11 weeks	20900 – 291000	23100 -233000	23. 7 - 130.4
11-16 weeks	6140 – 103000	20900 -103000	17.4 - 50.0
Weeks 16-21	4720 – 80100	6140 – 80100	4.67 - 33.3
21-39 weeks	2700 – 78100	2700 -78100	-

Table of average hCG norms for carrying twins:

Table of average values ​​of hCG after IVF with accustomed twins:

Free hCG β-subunit limits

Free hCG β-subunit measurement is more accurate in determining the risk of Down syndrome in an unborn child than measuring total hCG.

Norms for free β-hCG subunit in the first trimester:

Norms in ng / ml may vary in different laboratories, therefore the data indicated is not final, and in any case you should consult your doctor. If the result is indicated in MoM, then the norms are the same for all laboratories and for all analyzes: from 0.5 to 2 MoM.

If hCG is not normal, then:

1. If the free β-hCG subunit is higher than normal for your gestational age, or more than 2 MoM, then the child has an increased risk of Down syndrome.
2. If the free hCG β-subunit is below normal for your gestational age, or is less than 0.5 MoM, then the baby is at increased risk of Edwards syndrome.

PAPP-A norm

PAPP-A, or "pregnancy-associated plasma protein A" as it is called, is the second indicator used in biochemical screening of the first trimester. The level of this protein constantly increases during pregnancy, and deviations in the indicator may indicate various diseases in the unborn child.

Norm for PAPP-A depending on the duration of pregnancy:

Gestational period, weeks	HCG in ng/ml
8-9 weeks	0.17 - 1.54 mU/ml, or 0.5 to 2 MoM
9-10 weeks	0.32 - 2.42 mU/ml or 0.5 to 2 MoM
10-11 weeks	0.46 - 3.73 mU/ml, or 0.5 to 2 MoM
11-12 weeks	0.79– 4.76 mU/ml, or 0.5 to 2 MoM
12-13 weeks	1. 03 - 6.01 mU/ml, or 0.5 to 2 MoM
13-14 weeks	1.47 - 8.54 mU/ml, or 0.5 to 2 MoM

Norms in ng / ml may vary in different laboratories, therefore the data indicated is not final, and in any case you should consult your doctor. If the result is indicated in MoM, then the norms are the same for all laboratories and for all analyzes: from 0.5 to 2 MoM.

If PAPP-A is abnormal:

1. If PAPP-A is lower for your gestational age, or less than 0.5 MoM, your baby is at increased risk of Down syndrome and Edwards syndrome.
2. If PAPP-A is higher than normal for your gestational age, or more than 2 MoM, but other screening values ​​are normal, then there is no cause for concern.

Studies have shown that women with elevated PAPP-A levels during pregnancy are not at greater risk of fetal disease or pregnancy complications than other women with normal PAPP-A.

What if I am at high risk?

If your screening reveals an increased risk of having a baby with Down syndrome, then this is not a reason to terminate the pregnancy. You will be referred for a consultation with a geneticist who, if necessary, will recommend examinations: chorionic villus biopsy or amniocentesis

How to confirm or refute the screening results?

If you think that the screening was not done correctly, then you should be re-examined at another clinic, but for this you need to retake all the tests and undergo an ultrasound. This method is possible only if the gestational age at the time of the examination does not exceed 13 weeks and 6 days.

The doctor says I need an abortion. What to do?

Unfortunately, there are times when a doctor strongly recommends or even forces an abortion based on the screening results. Remember: no doctor has the right to such actions. Screening is not a definitive method for diagnosing Down syndrome and, based on poor results alone, a pregnancy should not be terminated.

Say that you want to consult a geneticist and undergo diagnostic procedures for Down syndrome (or other disease): chorionic villus biopsy (if you are 10-13 weeks pregnant) or amniocentesis (if you are 16-17 weeks pregnant).

The author of the article:

Ananyina Anna Alexandrovna

Obstetrician-gynecologist

Work experience since 2010
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Eat more foods rich in iron: beef tongue, liver, buckwheat and oatmeal, prunes, dried apricots, green apples, etc. But diet alone will not work to raise hemoglobin.
Medical therapy with iron supplements is required. If the problem is associated with insufficient intake of iron into the body, one set of drugs is needed, if with absorption, another. The doctor must select drugs.
Injection therapy may be required for more severe anemia.

If there are no contraindications, natural childbirth is possible. Only an obstetrician-gynecologist should decide on the possibility of EP.

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With an increase in the duration of pregnancy and the growth of the baby, the uterus increases - this can lead to increased tone. Sometimes tension arises in response to the movements of the child. Strong physical exertion, stress, overwork of a pregnant woman can also lead to increased tone.
In early pregnancy, uterine tone may be associated primarily with reduced progesterone production. In this case, the doctor prescribes the patient treatment with progesterone preparations.
Symptoms of increased tone
All pregnant women experience tone differently. Someone - like heaviness and tension in the lower abdomen. Others - as a pulling pain in the lumbar region. In the 2nd and 3rd trimesters of pregnancy, a woman can feel the tone by putting her hand on her stomach: the uterus becomes "stone", then relaxes.

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HCG rate during pregnancy. Table of hCG values ​​by week. Elevated HCG. Low HCG. HCG in ectopic pregnancy. hCG during IVF (hCG after replanting, hCG at 14 dpo).

hCG or beta-hCG or total hCG - human chorionic gonadotropin - a hormone produced during pregnancy. HCG is formed by the placenta, which nourishes the fetus after fertilization and implantation (attachment to the wall of the uterus).

• What is hCG (= beta-hCG)
• When to donate blood for hCG
• HCG norm. Deciphering the analysis of hCG. HCG level during pregnancy
• Normal HCG doubling time
• HCG norms by week. HCG table
• Low hCG. What does hCG below normal mean?
• Negative hCG or hCG indicative of non-pregnancy with missed period
• hCG and biochemical pregnancy
• hCG and ectopic pregnancy
• Elevated hCG. What can hCG levels above normal mean?
• HCG and multiple pregnancy. hcg and twins.
• Blister drift
• HCG test after embryo transfer. HCG for IVF
• hCG and ovarian hyperstimulation syndrome
• Elevated hCG levels in non-pregnant women and men
• How does hCG change after miscarriage, abortion, childbirth?
• What medications affect hCG levels?

HCG or beta-hCG or total hCG - human chorionic gonadotropin - a hormone produced during pregnancy. HCG is formed by the placenta, which nourishes the fetus after fertilization and implantation (attachment to the wall of the uterus). HCG is measured in mIU/mL (mile international units per milliliter).

HCG partially crosses the placental barrier. The level of hCG in newborns is approximately 1/400 of the level in maternal blood. And it is approximately 10-50 mIU / ml at birth. The half-life is 2-3 days. Thus, at 3 months of life, the level in newborns corresponds to the norm of hCG for an adult.

An increase in hCG in the blood can be detected a few days before the expected menstruation. The optimal time for a blood test to determine hCG is after a missed period.

A single determination of hCG cannot be used to diagnose miscarriage or ectopic pregnancy.

An hCG level of less than 5 mIU / ml indicates the absence of pregnancy or that the test was taken too early. The level of hCG is above 25 mIU / ml - about the presence of pregnancy.

On average, a doubling of hCG levels occurs every 36-72 hours. HCG levels peak at term 9-11 weeks of pregnancy (from the date of the last menstruation) and further decreases until the 15th week of pregnancy, remaining unchanged during the remainder of the pregnancy. In 85% of cases, the level of hCG in the early stages doubles every 48-72 hours. As pregnancy progresses, the doubling time for hCG levels increases to 96 hours.

HCG level Doubling time
1200 mIU/ml 48-72 hours
1200 – 6000 mIU/ml 72-96 hours
More than 6000 mIU/ml More than 96 hours

hcg calculator

At what hCG value should an ultrasound be done?

After reaching an hCG level of 1000 - 2000 mIU / ml, a fetal egg can be visualized by ultrasound. Since the level of hCG has a large variability, and the date of conception can be erroneous, the gestational age is determined by ultrasound or IVF data, but not by hCG.
A single determination of hCG is not enough, since it is important to evaluate the growth dynamics of the hormone every 48-72 hours.

These ranges are provided as a guide and should not be used to interpret a particular hCG assay.

• Not pregnant
• Error in calculating the gestational age
• Pregnancy arrest or miscarriage, biochemical pregnancy
• Ectopic pregnancy
• Threat of spontaneous abortion

It is necessary to repeat the analysis for hCG in 1-2 days, perhaps the pregnancy came later than expected. If the level of hCG does not rise, it is necessary to look for other reasons for the delay in menstruation.

The so-called "biochemical pregnancy" is a condition in which an increase in hCG above normal was detected, but the pregnancy did not continue to develop. The level of hCG in this case rises slightly, and then in a short time decreases to zero values.

An ectopic pregnancy is a pregnancy in which the fertilized egg is outside the uterine cavity. With an ectopic pregnancy, there may be pain in the lower abdomen, spotting. The level of hCG during an ectopic (ectopic) pregnancy may not increase as quickly and not as significantly as with a normally developing uterine pregnancy. However, the low level of hCG does not allow such a conclusion to be made unambiguously. Starting with an hCG level of 1000 mIU / ml, a fetal egg can be detected in the uterine cavity. With an hCG level of 2000 mIU / ml and the absence of a fetal egg in the uterine cavity during ultrasound, the likelihood of an ectopic pregnancy is significant.

• Error in calculation of gestational age
• Blister drift
• Multiple pregnancy
• Complications of pregnancy (preeclampsia)
• Maternal diabetes mellitus
• Taking synthetic gestagens
• Risk of fetal malformations

HCG and multiple pregnancy. hcg and twins.

The level of hCG in a multiple pregnancy is higher than in a single pregnancy, but the rate of increase in hCG is the same in both cases.

Vesicle drift is a rare complication of pregnancy in which the level of hCG will be significantly increased, on average 2 times higher than the average value for a given period. For example, the possible level of hCG with cystic mole for 36 days from the first day of the last menstruation can reach 200,000 mIU / ml, while with a normally developing pregnancy, hCG will be from 1,200 to 36,000 mIU / ml.

An hCG test is performed approximately 2 weeks after embryo transfer (12-14 days after transfer (dpp)). Usually the level of hCG at 14 dpo is more than 100 mIU / ml.

If the hCG level is less than 25 mIU / ml, pregnancy has not occurred. If the hCG level is more than 25, the test is repeated after 2 days, with the development of pregnancy, its level should increase. The hCG level will double approximately every 48 hours until 21 days after infusion.

Higher hCG values ​​(300-400 mIU / ml) are more likely to indicate multiple pregnancy.

In patients with ovarian hyperstimulation syndrome, hCG levels should be interpreted with caution. These patients may develop edema, which leads to thickening of the blood, which can lead to a false increase in the level of hCG, and when the blood composition is normal, to a false absence of an increase in the level of hCG.

The test for hCG is also included in the prenatal screening of the second trimester - an analysis that allows you to assess the risk of developing fetal defects.

Outside of pregnancy, hCG can be produced by the cells of some tumors (seminoma, testicular teratoma, neoplasms of the gastrointestinal tract (including pancreas, liver, colorectal cancer and stomach cancer).

With successful treatment of an hCG-producing tumor, the hCG level should decrease to normal.

In most cases, the level of hCG decreases. The half-life of hCG is 24-36 hours. The speed of reaching zero hCG values ​​depends on what exactly happened: spontaneous miscarriage, abortion, childbirth, curettage) and how high the hCG level was at the time of pregnancy loss. Doctors recommend continuing to assess hCG levels until levels are below 5 mIU/mL. If the hCG level remains high, you should consult a doctor.

The level of hCG is affected by drugs that contain hCG (Pregnil, Horagon).

• ToRCH infections and pregnancy

  What are ToRCH infections, what are the dangers of these infections during pregnancy, how and when is the examination performed, how to interpret the results. Perinatal infections account for approximately 2-3% of all congenital fetal anomalies.
  

• Pregnancy tests in the CIR Laboratories

  In our laboratory, you can undergo a complete examination at the onset of pregnancy, take tests at any time, and in our clinics you can conclude an agreement on pregnancy management.

• Online hCG calculator during pregnancy

  The hCG calculator is used to calculate the increase in hCG (the difference between two tests taken at different times).

  The increase in hCG is important for assessing the development of pregnancy. Normally, in the early stages of pregnancy, hCG increases by about 2 times every two days. As the hormone levels increase, the rate of increase decreases.

• False positive pregnancy test or why hCG is positive but not pregnant?

  When can a pregnancy test be positive?

• The norm of a complete blood count during pregnancy. Hemoglobin, platelets, hematocrit, erythrocytes and leukocytes during pregnancy. Clinical blood test during pregnancy. Hematological changes during pregnancy.

  Translation of materials from UpTodate.com
  A normal pregnancy is characterized by significant changes in almost all organs and systems to adapt to the requirements of the fetoplacental complex, including changes in blood tests during pregnancy.

• Risk assessment of pregnancy complications using prenatal screening

  Prenatal screening data allow assessing not only the risks of congenital pathology, but also the risk of other pregnancy complications: intrauterine fetal death, late toxicosis, intrauterine hypoxia, etc.

• Parvovirus B19 and parvovirus infection: what you need to know when planning and getting pregnant.

  What is a parvovirus infection, how is the virus transmitted, who can get sick, what is the danger of the virus during pregnancy, what tests are taken for diagnosis.
  

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  Obstetrics differs from other specialties in that during the physiological course of pregnancy and childbirth, in principle, it is not part of medicine (the science of treating diseases), but is part of hygiene (the science of maintaining health).

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