Vitamin k1 drops for newborns
Vitamin K at birth | Pregnancy Birth and Baby
Vitamin K at birth | Pregnancy Birth and Baby beginning of content5-minute read
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Key facts
- Vitamin K helps your baby’s blood to clot.
- Babies need more vitamin K than they get from their mother during pregnancy or from breast milk.
- Parents of all newborns are offered a vitamin K injection for their baby soon after birth.
- This helps prevent babies from becoming vitamin K deficient.
- Without the injection, they are at risk of developing a condition called Vitamin K Deficiency Bleeding (known as VKDB).
What is vitamin K?
Vitamin K is an essential vitamin, and has an important role in maintaining good health by helping blood to clot. Vitamin K helps prevent serious bleeding.
Why is vitamin K important for my baby?
Vitamin K helps your baby’s blood clot and prevents serious bleeding. Babies do not get enough vitamin K naturally from their mother during pregnancy. Breast milk also does not provide babies with enough levels of vitamin K. This can result in vitamin K deficiency in newborns.
If your baby has vitamin K deficiency, they are at risk of developing a disease called Vitamin K Deficiency Bleeding, or VKDB. While VKDB is rare, it can be very serious as it can cause babies to bleed excessively and may cause them to bleed into their brain. This condition may result in brain damage and even death.
How is vitamin K given?
Vitamin K is usually given as a single injection in your baby’s leg muscle shortly after birth. If you prefer that your baby does not get an injection, they can have liquid vitamin K drops into their mouth. It is important to note that oral vitamin K drops are not absorbed as well by the body than injected vitamin K, so 3 doses of oral vitamin K are needed. The first dose is given at birth, the second at 3 to 5 days of age and the third when they are 4 weeks old.
Vitamin K injections are preferred over the oral drops for all babies. Some babies aren’t able to have oral vitamin K, such as if the mother was taking certain medications while pregnant, or if your baby is premature, unwell, taking antibiotics or has diarrhoea.
Can all babies have vitamin K?
Yes, all babies can have vitamin K. If your baby is premature or very small, they might need a smaller dose of vitamin K. You can discuss this with your doctor.
How much does vitamin K cost?
Vitamin K injections or drops are free. The cost is covered by the government for all babies born in Australia.
Does vitamin K have any side effects? What should I look out for?
Vitamin K in newborns is not associated with any side effects, and has been given to Australian babies for more than 30 years. Studies have investigated whether there is an association between injected vitamin K and childhood cancers. Doctors and scientists have concluded that vitamin K injections are safe and beneficial for babies, and that there is no link between vitamin K and childhood cancer.
If your baby has not had a vitamin K injection or the full 3-dose course of vitamin K oral drops it is important that you look out for:
- unexplained bleeding or bruising
- showing signs of jaundice after they are 3 weeks old
If they show any of these symptoms, see your doctor or midwife immediately.
If your baby has liver problems, they may be at a higher risk of bleeding, even if they have had their recommended dose of vitamin K.
Does my baby need to have vitamin K?
It is your choice whether to give your baby vitamin K or not. However, giving vitamin K to your newborn is an easy way to prevent a very serious disease. Health authorities in Australia and throughout the world recommend giving vitamin K to all newborn babies — even babies who were born prematurely or are sick.
How do I get vitamin K for my baby?
During your pregnancy your doctor or midwife will talk to you about vitamin K, including the pros and cons of giving your baby vitamin K by injection or by mouth. Your doctor or midwife will then note this on your file. Your baby will receive vitamin K soon after birth by a doctor or a midwife, based on your decision.
If you have chosen to give your baby vitamin K by mouth then your baby will need to receive 2 more doses after the dose they receive at birth. The second dose can be given in hospital at the same time as your baby has their newborn screening test, or by your local doctor or healthcare worker. It is important to remember to arrange your baby’s third dose when they are 4 weeks old. This important final dose can also be given by your doctor or health care worker.
If you are having a home birth, be sure to discuss giving your baby vitamin K with your midwife. Homebirth midwives are required to have all essential equipment available for a planned home birth, including vitamin K injections.
Sources:
Australian Government, National Health and Medical Research Council (Vitamin K for Newborn Babies), South Australian Neonatal Medication Guidelines (Vitamin K), NSW Health (Having a baby - Labour and birth), SA Health (Planned Birth at Home in SA. 2018 Clinical Directive), The Royal Women Hospital Australia (Tests and Medicines for Newborn Babies)Learn more here about the development and quality assurance of healthdirect content.
Last reviewed: June 2022
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Vitamin K for newborns | NHMRC
Vitamin K helps blood to clot and is essential in preventing serious bleeding in infants. Vitamin K deficiency bleeding can be prevented by the administration of vitamin K soon after birth. By the age of approximately six months, infants have built up their own supply of vitamin K.
Read more on NHMRC – National Health and Medical Research Council website
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Bio-K-Mulsion Oral Vitamin K - In His Hands Birth Supply
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Bio-K-Mulsion Oral Vitamin K
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- UPC:
- 780053000621
- Availability:
- Not for resale. Please contact us to order more than 6.
- Maximum Purchase:
- 6 units
See details
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- Shipping and Returns
- Warranty Information
This item can be defective if frozen or left in the heat. Please make arrangements for the item to be kept at room temperature after delivery. We are unable to replace bottles which arrive frozen or have been left in the heat.
Bio-K-Mulsion Oral Vitamin K (Emulsified Vitamin K) Dietary Supplement
Bio-K-Mulsion® supplies vitamin K1 (500 mcg per drop) in an emulsified liquid form to aid in the uptake and utilization of this important vitamin. Bio-K-Mulsion® is an oil-in-water emulsion. Vitamin K oil has been dispersed into microscopic particles to aid with absorption and assimilation.
By Biotics Research Corporation
- 1 Fluid Ounce (30 mL)
- This product is gluten and dairy free.
- Stock expires in 5-6 months after purchase.
- Dietary Supplement (Emulsified Vitamin K)
Ingredients
Vitamin K (As K1-phytonadione) - 1 Drop (0.04 mL) -
Serving size 500 mcg.
1 drop = .5 milligram
% Daily Value 417%
Other ingredients
Water, gum arabic and sesame seed oil.
Adult dosage recommendation
"One (1) drop each day as a dietary supplement or as otherwise directed by a healthcare professional" Be sure to consult with your midwife or healthcare professional before taking or administering this supplement.
Newborn dosage
For families looking for one possible dosage schedule regarding the oral Vitamin K, the following schedule is a guide recommended by many midwives. There are varying schedules; check with your healthcare provider and see what schedule and dosage they recommends for the oral drops.
Day 1 of Life: 1 drop
Day 7 of Life: 1 drop
Day 21 of Life: 1 drop
One easy way to administer the drops is via the parent’s finger swabbed onto the newborn’s inner cheek inside the mouth. Breastfeeding mothers can consume the rest of the Vitamin K drops to boost their own stores after birth.
Oral Vitamin K may be contraindicated in the case of the baby undergoing a surgical procedure, such as circumcision.
Manufacture Product Warnings
Caution: Those taking warfarin should avoid supplementation with vitamin K unless specifically recommended and monitored by their physician. Pregnant and nursing women should avoid supplemental intakes higher than the RDA (65 mcg) unless specifically recommended and monitored by their physician. KEEP OUT OF REACH OF CHILDREN.
FDA Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease;
Not for resale
Orders made with the intention to resell this item will be canceled.
Shipping and Returns
Shipping cost is based on weight. Just add products to your cart and use the Shipping Calculator to view the different options.
We offer free shipping on orders over $99 shipping to the lower 48 states
We want you to be 100% satisfied with your purchase. Most items in new condition can be returned or exchanged within 90 days of purchase.
Read more about our shipping options here and returns here.
This item can be defective if frozen or left in the heat for an extended period Please make arrangements for the item to be kept at room temperature after delivery. We are unable to replace bottles which arrive frozen or have been left in the heat for an extended period.
-
Description
This item can be defective if frozen or left in the heat. Please make arrangements for the item to be kept at room temperature after delivery. We are unable to replace bottles which arrive frozen or have been left in the heat.
Bio-K-Mulsion Oral Vitamin K (Emulsified Vitamin K) Dietary Supplement
Bio-K-Mulsion® supplies vitamin K1 (500 mcg per drop) in an emulsified liquid form to aid in the uptake and utilization of this important vitamin. Bio-K-Mulsion® is an oil-in-water emulsion. Vitamin K oil has been dispersed into microscopic particles to aid with absorption and assimilation.
By Biotics Research Corporation
- 1 Fluid Ounce (30 mL)
- This product is gluten and dairy free.
- Stock expires in 5-6 months after purchase.
- Dietary Supplement (Emulsified Vitamin K)
Ingredients
Vitamin K (As K1-phytonadione) - 1 Drop (0.04 mL) -
Serving size 500 mcg.
1 drop = .5 milligram
% Daily Value 417%
Other ingredients
Water, gum arabic and sesame seed oil.
Adult dosage recommendation
"One (1) drop each day as a dietary supplement or as otherwise directed by a healthcare professional" Be sure to consult with your midwife or healthcare professional before taking or administering this supplement.
Newborn dosage
For families looking for one possible dosage schedule regarding the oral Vitamin K, the following schedule is a guide recommended by many midwives. There are varying schedules; check with your healthcare provider and see what schedule and dosage they recommends for the oral drops.
Day 1 of Life: 1 drop
Day 7 of Life: 1 drop
Day 21 of Life: 1 dropOne easy way to administer the drops is via the parent’s finger swabbed onto the newborn’s inner cheek inside the mouth. Breastfeeding mothers can consume the rest of the Vitamin K drops to boost their own stores after birth.
Oral Vitamin K may be contraindicated in the case of the baby undergoing a surgical procedure, such as circumcision.
Manufacture Product Warnings
Caution: Those taking warfarin should avoid supplementation with vitamin K unless specifically recommended and monitored by their physician. Pregnant and nursing women should avoid supplemental intakes higher than the RDA (65 mcg) unless specifically recommended and monitored by their physician. KEEP OUT OF REACH OF CHILDREN.
FDA Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease;
Not for resale
Orders made with the intention to resell this item will be canceled.
-
Shipping and Returns
Shipping and Returns
Shipping cost is based on weight. Just add products to your cart and use the Shipping Calculator to view the different options.
We offer free shipping on orders over $99 shipping to the lower 48 states
We want you to be 100% satisfied with your purchase. Most items in new condition can be returned or exchanged within 90 days of purchase.
Read more about our shipping options here and returns here.
Why are newborns given vitamin K injections?
At Mother and Child clinics, we recommend vitamin K injections for all newborns to prevent hemorrhagic disease.
Hemorrhagic disease (HRD), or vitamin K-deficient hemorrhagic syndrome, is a disease manifested by increased bleeding in newborns and children during the first months of life, due to a deficiency of blood coagulation factors, the activity of which depends directly on vitamin K.
Vitamin K of plant origin, which is called vitamin K 1 or phylloquinone, enters the body with food - green vegetables, vegetable oils, dairy products. Another form of vitamin K, vitamin K2, or menaquinone, is of bacterial origin. Vitamin K 2 is mainly synthesized by the intestinal microflora, which is extremely poor in newborns.
In healthy newborns, the level of vitamin K-dependent coagulation factors in blood plasma is 30-60% of that in adults. Their concentration increases gradually and reaches the level of adults by the sixth week of life. In almost all healthy full-term infants in the first five days of life, there is a decrease in the level of procoagulants, physiological anticoagulants and plasminogen.
For the newborn, the only source of vitamin K is mother's milk, formula or medicine. Moreover, the amount of vitamin K received by a child depends on the type of feeding. The level of vitamin K 1 in breast milk ranges from 1 to 10 µg/l, on average 2-2.5 µg/l, which is significantly lower than in artificial milk formulas (about 50 µg/l in mixtures for full-term babies; 60 -100 mcg / l - in mixtures for premature babies). Thus, newborns, due to their physiological characteristics of the coagulation system and vitamin K metabolism, are predisposed to the development of vitamin K-deficient hemorrhagic syndrome.
PLEASE NOTE! Poor blood clotting is a condition dangerous for the body, in which bleeding or hemorrhage is noted in various organs. This pathology develops in 0.25-0.5% of newborns.
RISK FACTORS FOR THE DEVELOPMENT OF RHD
• Exclusive breastfeeding
• Lack of prophylactic administration of vitamin K immediately after birth
• Chronic fetal hypoxia and asphyxia at birth
• Giving birth
• Intrauterine development delay
• Giving birth by cesarean section
• Nedness
• The use of a wide range of
• Long -term parenteral nutrition in the conditions of inadequate supply of
• Diseases and condition of the child that contribute impaired synthesis and absorption of vitamin K
• malabsorption syndrome (cystic fibrosis, diarrhea with fat malabsorption lasting more than one week)
• short bowel syndrome;
• cholestasis;
• pre-eclampsia
• maternal diseases (liver and intestinal diseases).
Vitamin K for the prevention of bleeding in newborns
Vitamin K is required for the synthesis of blood coagulation factors in the liver, which include factors II (prothrombin), VII, IX and X, as well as anticoagulant proteins C and S. In newborns at term, especially those who are exclusively breastfed may develop vitamin K deficiency and therefore associated bleeding because breast milk contains very low levels of vitamin K.
Problematic and management of bleeding in preterm infants
Premature infants are potentially at even higher risk of developing vitamin K deficiency-associated bleeding due to delayed feeding and subsequent delay in colonization of their gastrointestinal tract by microflora involved in vitamin K production, use of antibacterial drugs, as well as due to inferior liver function and hemostasis. The administration of vitamin K preparations to prevent bleeding associated with vitamin K deficiency has been described to some extent in both term and premature infants. It is indicated that a single intramuscular injection of 1 mg of a vitamin K preparation after birth is effective in this regard.
There is evidence that not only injectable but also oral vitamin K supplementation improves biochemical parameters of coagulation in infants. However, none of these approaches has been studied in the framework of randomized trials for bleeding of various periods (early, classic and late) after birth. Concern has also been expressed about the prophylactic use of vitamin K preparations due to the presence of phenol in their composition, which has potentially carcinogenic properties. A systematic review of the literature did not reveal an increased risk of malignant neoplasms in children after intramuscular injections of vitamin K preparations, so the American Academy of Pediatrics (AAP) continues to recommend prophylactic intramuscular administration of 0.5-1 mg of a vitamin K preparation to infants after birth to prevent early, classic and late form of associated bleeding in term babies.
Recommendations for the use of vitamin K supplements in preterm infants are less specific because associated bleeding has not been widely discussed in the literature. This may be partly due to the fact that most preterm infants in intensive care units are routinely given prophylactic vitamin K supplementation, and that parenteral nutrition is started early, providing preterm infants with more than enough vitamin K. However, there are many reasons to believe that preterm infants may be at greater risk of associated bleeding, and that these bleeding may be more important, especially in relation to the risk of intraventricular hemorrhage.
Based on this, scientists in the United States of America conducted a systematic review of studies to determine the effect of vitamin K supplementation in preventing vitamin K deficiency-associated bleeding in preterm infants. The results of this work were published on February 5, 2018 in the Cochrane Database of Systematic Reviews.
Trial and participant selection criteria
Searched Cochrane Central Register of Controlled Trials, World Health Organization International Clinical Trials Registry Platform, and electronic databases MEDLINE, PubMed, Embase, CINAHL, and others. Scientists reviewed randomized and quasi-randomized controlled trials of any vitamin K supplement given to preterm infants. At the same time, intramuscular and intravenous injections, as well as oral use of various vitamin K preparations in various dosages, were compared with non-intervention. As a result, 899 records, of which scientists analyzed 7 full-text studies.
Primary outcomes
- Any bleeding.
- Any serious bleeding requiring immediate blood transfusion.
- Gastrointestinal bleeding.
- Intracranial hemorrhages.
*All types of bleeding in the primary outcomes were studied in two subgroups: infants less than 7 days of age and older.
Secondary outcomes included laboratory parameters (at and after the first week of life) and potential side effects of prophylactic vitamin K supplementation.
Findings and conclusions from a systematic review Compared with non-intervention, and in only one study, scientists have considered various dosages and routes of administration of vitamin K supplements in preterm infants. The results obtained indicate that the majority of infants who received intramuscular or intravenous injections of vitamin K preparations at a dosage of 0.
2 mg had supraphysiological levels of vitamin K in the blood on the 5th day of life.At the same time, it was found that intravenous administration of 0.2 mg of the drug is slightly more effective than intramuscular injection of 0.5 mg, according to analyzes of the level of vitamin K in the blood at the end of the observation. However, there were no significant differences between the use of 0.2 mg intravenous, 0.2 and 0.5 mg intramuscular vitamin K in relation to general pathologies associated with prematurity, including other clinical bleeding, sepsis, ventriculomegaly, as well as in relation to mortality. .
Another study looked at blood concentrations of vitamin K in infants 22 to 32 weeks of gestational age who received either 1 mg or 0.5 mg of a vitamin K preparation as part of prophylaxis, with the dosage determined by the attending physician at the infants' admission to the unit neonatal intensive care. Infants were exclusively breastfed, with the exception of individual cases when this was not possible.