Hormone levels in pregnancy 6 weeks
hCG levels | Pregnancy Birth and Baby
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Human chorionic gonadotropin (hCG) is a hormone normally produced by the placenta. If you are pregnant, you can detect it in your urine. Blood tests measuring hCG levels can also be used to check how well your pregnancy is progressing.
Confirming pregnancy
After you conceive (when the sperm fertilises the egg), the developing placenta begins to produce and release hCG.
It takes about 2 weeks for your hCG levels to be high enough to be detected in your urine using a home pregnancy test.
A positive home test result is almost certainly correct, but a negative result is less reliable.
If you do a pregnancy test on the first day after your missed period, and it’s negative, wait about a week. If you still think you might be pregnant, do the test again or see your doctor.
hCG blood levels by week
If your doctor needs more information about your hCG levels, they may order a blood test. Low levels of hCG may be detected in your blood around 8 to 11 days after conception. hCG levels are highest towards the end of the first trimester, then gradually decline over the rest of your pregnancy.
The average levels of hCG in a pregnant woman’s blood are:
3 weeks | 6 – 70 IU/L |
4 weeks | 10 - 750 IU/L |
5 weeks | 200 - 7,100 IU/L |
6 weeks | 160 - 32,000 IU/L |
7 weeks | 3,700 - 160,000 IU/L |
8 weeks | 32,000 - 150,000 IU/L |
9 weeks | 64,000 - 150,000 IU/L |
10 weeks | 47,000 - 190,000 IU/L |
12 weeks | 28,000 - 210,000 IU/L |
14 weeks | 14,000 - 63,000 IU/L |
15 weeks | 12,000 - 71,000 IU/L |
16 weeks | 9,000 - 56,000 IU/L |
16 - 29 weeks (second trimester) | 1,400 - 53,000 IU/L |
29 - 41 weeks (third trimester) | 940 - 60,000 IU/L |
The amount of hCG in your blood can give some information about your pregnancy and the health of your baby.
- Higher than expected levels: you may have multiple pregnancies (for example, twins and triplets) or an abnormal growth in the uterus
- Your hCG levels are falling: you may be having a loss of pregnancy (miscarriage) or risk of miscarriage
- Levels that are rising more slowly than expected: you may have an ectopic pregnancy – where the fertilised egg implants in the fallopian tube
hCG levels and multiple pregnancies
One of the ways of diagnosing a multiple pregnancy is by your hCG levels. A high level may indicate you are carrying multiple babies, but it can also be caused by other factors. You will need an ultrasound to confirm that it’s twins or more.
Levels of hCG in your blood don’t provide a diagnosis of anything. They can only suggest that there are issues to look into.
If you have any concerns about your hCG levels, or wish to know more, speak to your doctor or maternity healthcare professional. You can also call Pregnancy, Birth and Baby to speak to a maternal child health nurse on 1800 882 436.
Sources:
UNSW Embryology (Human Chorionic Gonadotropin), Elsevier Patient Education (Human Chorionic Gonadotropin test), SydPath (hCG (human Chorionic Gonadotrophin), Pathology Tests Explained (Human chorionic gonadotropin), NSW Government Health Pathology (hCG factsheet)Learn more here about the development and quality assurance of healthdirect content.
Last reviewed: December 2020
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HCG Levels in Pregnancy & hCG Levels Chart by Week
Human chorionic gonadotropin, or hCG for short, is often referred to as “the pregnancy hormone” because it’s present in large quantities during pregnancy. And it is, after all, the hormone that many at-home pregnancy tests are designed to detect! Find out more about what hCG is, when it’s detectable by at-home pregnancy tests, and what the typical hCG levels are for each of the early weeks of pregnancy.
What Is hCG and When Does Your Body Start Producing It?
Human chorionic gonadotropin (hCG) is known as the pregnancy hormone, as your body produces it in large amounts when you’re pregnant.
Although you can have low levels of hCG in your body at any time, the levels of this hormone tend to rise sharply early on in your pregnancy for two reasons:
About 10 days after conception, the fertilized egg attaches to the lining of your uterus and your body starts to make hCG. Over the next week or so, hCG levels will increase.
At about 4 weeks pregnant, the egg—now called an embryo—implants further into the uterus and begins to produce even more hCG, which triggers increased productions of other hormones like estrogen and progesterone.
Together, these hormones help build the lining of the uterus and send signals to the ovaries to stop releasing eggs, ultimately stopping your period.
During these early weeks of pregnancy, you may not show any outward signs of being pregnant and you may not even suspect that you’re pregnant! You may, however, experience implantation bleeding when the fertilized egg attaches to the lining of the uterus (as described above). This is normal and may resemble spotting or a light period.
When Can Pregnancy Tests Detect hCG?
Home pregnancy tests often work by detecting hCG in your urine. All of these over-the-counter pregnancy tests work a little differently, so check the instructions in or on the box. Keep in mind that hCG levels increase over time, so at-home tests are more accurate as your pregnancy progresses. Therefore, a home-pregnancy test that’s taken too early might not detect low levels of hCG and could produce a false negative, meaning the result is negative when you’re actually pregnant. If you’re wondering when to take an at-home pregnancy test, try one of the following timelines:
You might try taking a pregnancy test about three to four weeks after the first day of your last period, as this is when the levels of hCG in your urine will have increased enough to be detectable.
You could wait until around the time you miss your next period, which could be the initial clue that you may be pregnant anyway! By then, the levels of hCG are detectable.
A blood test is the most accurate way to detect hCG levels, because more of the pregnancy hormone is present in the blood than in the urine. Plus, blood tests need less of the hCG hormone to detect a pregnancy, as explained below:
Blood tests. Pregnancy blood tests can detect hCG hormone levels as low as 5 to 10 mIU/mL.
Urine tests. At-home urine tests require higher levels of hCG to detect a pregnancy, typically at least 20 mIU/mL.
If your home pregnancy test is positive, your healthcare provider may offer a blood test to check your hCG levels. The results can help your provider confirm your pregnancy and determine how far along you are.
If you’ve just found out you’re pregnant, you can get an estimate of your due date with our Due Date Calculator using either the date of conception or the date of the first day of your last menstrual period!
hCG Levels Chart by Week
The week-by-week chart below will give you an idea of how your hCG levels may rise during the first trimester, and then dip slightly during the second trimester. Keep in mind that, if you want your hCG blood test results explained in more detail, your healthcare provider is the best person to ask.
What Does It Mean if You Have High or Low hCG Levels?
It’s important to remember that every pregnancy is different, and you may have lower or higher levels of hCG hormone than what’s indicated in the week-by-week chart above. Most likely, there’s no cause for concern, but your healthcare provider will help you understand what these levels mean.
Low Levels of hCG
Low levels of hCG are normal for non-pregnant women and men. Normally, hCG levels would be less than 5 mIU/mL and less than 2 mIU/mL, respectively, for these groups. If you’re pregnant and experience low hCG levels, it’s important to look at your entire pregnancy as a whole. Your healthcare provider will consider all the factors of your pregnancy to determine why you might be experiencing lower-than-normal levels of hCG. If your provider suspects anything like an ectopic pregnancy, they may perform additional tests to rule it out.
High Levels of hCG
Likewise, high levels of the hCG hormone might not indicate anything out of the ordinary. However, a higher-than-normal level of hCG may be a sign that you’re having twins or triplets! Again, your healthcare provider will work with you to determine an appropriate course of action, if any is needed. Lower- or higher-than-normal levels of the hCG hormone during your pregnancy might not indicate anything unusual. However, it’s always a good idea to follow up with your healthcare provider as a precaution, regardless of any questions or concerns you have. Read more about other pregnancy symptoms not to ignore.
The Bottom Line
The hCG hormone plays an important role in your pregnancy, and the changing levels of this hormone are just one of many transformations your body will experience as your baby develops. Although hormonal changes can make you feel a little off from time to time during your pregnancy, try to take these as reassurance that your baby is growing, and you’re getting closer and closer to the day you finally get to meet them. In the meantime, prepare for your baby’s arrival and get rewards on all your diapers and wipes purchases with the Pampers Club app! Ready to share your pregnancy news with friends and family? Get creative pregnancy announcement ideas in the video below!
Hormonal studies during pregnancy / Nyanya.ru
02/27/2012
Nona Hovsepyan, Consultant Physician, Independent Laboratory INVITRO
Why is it necessary to control the level of hormones?
Hormones are amazing biologically active substances that affect not only the state of health, but also the inner world of a person. Nature provides that in the female body immediately after conception, special pregnancy hormones are activated, which not only help the baby to fully develop, but also set up the expectant mother for the desired motherhood, teach them to love the baby growing inside and get used to taking care of him. nine0003
During the period of expectation of a baby, serious changes occur in the whole body of a woman, especially her hormonal background. Changes occur throughout the endocrine system. The body of the future mother, completely rebuilding, creates the conditions for the bearing and normal development of the baby, and from the first days of pregnancy begins to prepare for childbirth.
All hormonal indicators of the future mother's body play a huge role - namely, they are the most important indicators of fetal development. Therefore, the level of hormones is necessarily monitored by the attending physician with the help of special examinations - prenatal screenings, which a woman needs to undergo at least 2 times: in the first trimester (11-12 weeks) and in the second trimester (16-19weeks). Let's figure out what indicators are included in this mandatory examination, what the increase or decrease in the level of a particular hormone indicates, and what their role is.
Hormones that the body of the unborn baby "produces"
HCG. This is human chorionic gonadotropin, a hormone that is actively produced by the cells of the chorion (fetal membrane) immediately after it attaches to the wall of the uterus. The "production" of this hormone is vital for the preservation and maintenance of pregnancy! It is hCG that controls the production of the main pregnancy hormones - estrogen and progesterone. With a serious lack of hCG, the fertilized egg is detached from the uterus, and menstruation occurs again - in other words, a spontaneous miscarriage occurs. Normally, the concentration of hCG in the blood of the expectant mother is constantly growing, reaching a maximum by the 10-11th week of pregnancy, then the concentration of hCG gradually decreases to remain unchanged until the very birth. nine0003
Testing for hCG during pregnancy plays a huge role.
Firstly, an analysis of the level of hCG in the blood can confirm that you will become a mother already 5-6 days after conception. This is much earlier and, most importantly, much more reliable than using conventional rapid tests.
Secondly, the test is needed to determine the exact gestational age. Very often, the expectant mother cannot give the exact date of conception, or she calls it, but incorrectly. At the same time, certain indicators of growth and development correspond to each period, deviations from the norm may indicate the occurrence of complications. nine0003
Thirdly, the level of hCG in the blood can quite accurately “tell” whether your baby is developing correctly.
An unplanned increase in the level of hCG usually occurs with multiple pregnancy, preeclampsia, taking synthetic gestagens, diabetes in the expectant mother, and may also indicate some hereditary diseases in the baby (for example, Down's syndrome) and multiple malformations. An abnormally low level of hCG can be a sign of an ectopic and non-developing pregnancy, fetal growth retardation, the threat of spontaneous abortion, and chronic placental insufficiency. nine0003
However, do not rush to sound the alarm: increased or decreased values may also indicate that the gestational age was initially set incorrectly. Your doctor will help you interpret the test results correctly.
Placental lactogen and free estriol. Controlling the level of these hormones is extremely important for assessing the risk of developing hereditary chromosomal abnormalities in an unborn baby (these are Down, Edwards, Turner, Patau syndromes, neural tube defects, etc.) nine0003
Free estriol is "produced" by the placenta. This hormone improves blood flow through the vessels of the uterus, and also contributes to the development of the ducts of the mammary glands, preparing the body of the expectant mother to feed the baby. The level of free estriol changes in any pathological conditions:
- with fetoplacental insufficiency, when the normal blood flow and nutrition in the placenta changes;
- for fetal growth retardation; nine0036 for suspected post-term pregnancy.
Placental lactogen (PL) is also “produced” by the placenta and can be detected in the blood of the expectant mother as early as 5-6 weeks of pregnancy. It reaches its maximum value by 37-38 weeks, then the hormone level gradually decreases. However, the level of PL must be monitored throughout the entire period of pregnancy - first of all, this is necessary to assess the condition of the placenta and timely diagnosis of placental insufficiency. A sharp decrease in the level of PL by more than 2 times (compared to the average level in accordance with the gestational age) may indicate a delay in fetal development. In this case, it is necessary to take emergency measures to prevent a decrease in the level of PL by 80 percent or more - this can lead to the death of the baby. nine0033
Pregnancy hormones
Estradiol and progesterone. Hormonal studies necessarily include tests for the level of progesterone and estradiol. It is they who take care of your unborn baby, maintaining the normal course of pregnancy, which is why they are called the main hormones of gestation (pregnancy).
Estradiol is produced by the ovaries and during pregnancy also by the placenta. During pregnancy, the level of the hormone rises sharply, and it is not surprising - estradiol is "responsible" for the normal course of pregnancy. In the early stages, the concentration of this hormone evaluates the functioning of the placenta. A decrease in the level of estradiol indicates a serious threat of abortion. nine0003
By the way, it is under the influence of this hormone that a woman feels a natural desire to “build a nest”, arrange everything and prepare for the birth of a baby. Before childbirth, the concentration of the hormone in the body of the expectant mother reaches its “peak”, which is also due to natural causes - estradiol, acting as the strongest natural pain reliever, helps to make the process of giving birth to a baby less painful.
Progesterone is also the main “pregnancy hormone”, the main task of which is to maintain pregnancy and create the necessary conditions for the development of the fetus. A normal level of progesterone is necessary for conception to occur. Together with estrogens, the hormone promotes the attachment of a fertilized egg to the endometrium and carefully reduces the increased tone of the uterus, preventing miscarriage. During the bearing of the baby, progesterone stimulates the growth and maturation of the mammary glands, “preparing” the body of the expectant mother for breastfeeding, and psychologically, it calms her down and morally supports her. Unfortunately, this hormone also has "side" effects that are familiar to every pregnant woman - this is increased drowsiness, nausea, frequent urination, soreness and swelling of the breast. nine0003
With a lack of progesterone, pregnancy can occur with serious complications. Hormone deficiency must be urgently replenished, otherwise the risk of non-developing pregnancy and miscarriage increases.
Important! Testing for estradiol and progesterone levels is carried out both during pregnancy and in preparation for the birth of a child, this is especially necessary in cases where a woman has already had a miscarriage.
Thyroid hormones
The normal functioning of the thyroid gland of the expectant mother plays an important role in the development of the baby. The corresponding hormones (TSH, T3 and T4) can also “tell” about the presence of hypo- or hyperfunction of the gland.
Maternity hormones
Pituitary hormones (an endocrine gland located in the hypothalamic part of the brain) also play an indispensable role while waiting for a baby. During childbirth, the pituitary gland releases the hormone oxytacin into the blood, which stimulates uterine contractions. And after childbirth, an active synthesis of the hormone prolactin begins, which is “responsible” for lactation. With a lack of prolactin, a woman simply would not be able to fully feed her baby with breast milk. nine0003
In addition, prolactin and oxytacin are also called "maternity hormones", because thanks to them, the mother's heart is filled with tenderness, she feels the pleasure of feeding and communicating with the child, which binds her to the baby even more. These hormones, in fact, provide a magical “transformation” of a woman into a mother - under their influence, priorities change dramatically, study, work, career and personal success fade into the background, and the main place in a woman’s heart is occupied by a small native creature. It is believed that the more a woman has these same "maternity hormones", the stronger her desire to constantly be with the baby, feel his warmth, take care of him. However, one should not expect that this “transformation” will happen as if by magic: normally, the level of hormones in a woman’s body changes gradually, so that her psyche has time to prepare for the changes without stress. The main thing during pregnancy is to make every effort to endure a strong and healthy baby. nine0003
Hormones during pregnancy - advice from a gynecologist in Simferopol
Nausea, chest pain, appetite for pickled cucumbers - all this is the action of hormones. During pregnancy, you are under their strong influence.
How do they work? Until you became pregnant, most of the hormones in your body were produced by endocrine glands such as the thyroid gland. Now, many of them also form in the placenta, which is inside the uterus. Immediately after the birth of the baby, the placenta is excreted from the body and pregnancy hormones are no longer needed. nine0003
Hormones cause nausea during pregnancy.
The culprit is human chorionic gonadotropin , which is produced by the embryo and then by the placenta. It is the presence of this hormone in the urine that leads to a positive pregnancy test result. In addition, chorionic gonadotropin increases the production of another hormone, progesterone , and stops the menstrual cycle.
Feeling of happiness.
Endorphins - these hormones are your biggest allies. These are natural painkillers and calming hormones. They work like morphine. They are called happiness hormones because they are the reason you expect a baby with joy, regardless of nausea and other pregnancy ailments. The source of endorphins is in the brain, where they are produced until the end of labor. The highest concentration of endorphins at the time of childbirth. Thanks to them, the pain becomes weaker, and the stress associated with childbirth is not so tiring. After childbirth, the level of endorphins drops sharply. This is probably the cause of a mild form of postpartum depression. nine0003
Sexual attraction.
Estrogens , which affect your sex drive, are first produced by the ovaries and then by the placenta. Estrogen production rises rapidly at the beginning of pregnancy. Thanks to estrogen, you feel that the desire for intimacy in the first trimester of pregnancy increases. Estrogens increase the blood supply to the breasts, vagina, vulva, and clitoris, which become especially sensitive. It is interesting! Thanks to pregnancy hormones, sex in the second trimester of pregnancy can be the best in a lifetime, according to scientists! nine0003
They relax muscles and prevent spasms. This is the influence of one of the most important pregnancy hormones: progesterone . Before pregnancy, it was produced, like estrogens, by the ovaries, now this function has passed to the placenta. Progesterone is responsible for most of the changes in your body during pregnancy (including fever, increased breathing). It relaxes the smooth muscles of the uterus and protects against miscarriage.
Pregnancy hormones prepare you for childbirth. nine0096
Preparing for childbirth is the merit of relaxin . Under its influence, the joints of the pelvic bones relax, soften the cervix and increase the elasticity of the surrounding ligaments, so that your uterus will grow, and your child will be able to pass through the birth canal.
Labor spasms.
Prostaglandins and oxytocin are the hormones that most support the final stages of pregnancy. The rising level of oxytocin is responsible for the development of the maternal instinct. In the last trimester, you begin to feel uterine contractions stimulated by prostaglandins. If you have sex, you can speed up labor because prostaglandins are also found in male semen. Oxytocin stimulates predictive uterine contractions or Braxton-Hicks contractions and then the corresponding labor contractions. In some situations, it stimulates labor and accelerates the passage of the placenta. nine0003
Help in the first days after childbirth.
Two more hormones, prolactin and placental lactogen , will allow you to breastfeed your baby. Thanks to them, the breasts begin to secrete colostrum (the first very nutritious food that can be excreted as early as the 19th week of pregnancy). Your body will produce it within days of giving birth.